mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS. (Q33931904)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20335217%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS (English)

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29 January 2020

1

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8

Angus W Thomson

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29 January 2020

author name string

Jon Cardinal

2

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29 January 2020

Camila Macedo

3

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29 January 2020

Brian R Rosborough

4

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29 January 2020

Tina L Sumpter

5

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29 January 2020

David A Geller

6

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29 January 2020

Diana Metes

7

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29 January 2020

language of work or name

English

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publication date

24 March 2010

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29 January 2020

number of pages

12

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inferred from page(s)

published in

Blood

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29 January 2020

volume

115

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issue

23

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29 January 2020

page(s)

4758-4769

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The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)

29 January 2020

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1 reference

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Immunoregulatory functions of mTOR inhibition.

5 July 2018

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mTOR and the control of whole body metabolism

5 July 2018

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An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

5 July 2018

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Impact of mammalian target of rapamycin inhibition on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic hematopoietic cell transplantation

5 July 2018

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IL-12R beta 2 promotes the development of CD4+CD25+ regulatory T cells

5 July 2018

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Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

5 July 2018

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5 July 2018

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IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells

5 July 2018

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Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells

5 July 2018

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Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells

5 July 2018

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Nuclear GSK-3beta inhibits the canonical Wnt signalling pathway in a beta-catenin phosphorylation-independent manner.

5 July 2018

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Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells

5 July 2018

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5 July 2018

Expanding mTOR signaling

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Tolerogenic dendritic cells and the quest for transplant tolerance

5 July 2018

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Defining the role of mTOR in cancer

5 July 2018

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5 July 2018

The two TORCs and Akt.

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Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs

5 July 2018

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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

5 July 2018

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IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

5 July 2018

1 reference

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Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

5 July 2018

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Negative regulation of toll-like receptor-mediated immune responses

5 July 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

5 July 2018

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Dendritic cell-mediated T cell polarization

5 July 2018

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Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

5 July 2018

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Rapamycin inhibits IL-4--induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo

5 July 2018

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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

5 July 2018

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Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation

5 July 2018

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

5 July 2018

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5 July 2018

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The TSC-mTOR signaling pathway regulates the innate inflammatory response

29 October 2018

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Different profile of gene expression of cytokines in peripheral blood mononuclear cells of transplant recipients treated with m-TOR inhibitor and calcineurin inhibitor

29 October 2018

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29 October 2018

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Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kappa B activation and IFN-beta synthesis downstream of Toll-like receptor 3 and 4.

29 October 2018

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Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.

29 October 2018

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Rapamycin-treated, alloantigen-pulsed host dendritic cells induce ag-specific T cell regulation and prolong graft survival

29 October 2018

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Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression

29 October 2018

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Rapamycin inhibits macropinocytosis and mannose receptor-mediated endocytosis by bone marrow-derived dendritic cells

29 October 2018

1 reference

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Generation, persistence, and modulation of Th0 effector cells: role of autocrine IL-4 and IFN-gamma.

29 October 2018

1 reference

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FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

29 October 2018

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12 December 2020

Interstitial pneumonitis associated with sirolimus therapy in renal-transplant recipients

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12 December 2020

Cutting edge: polarized Th cell response induction by transferred antigen-pulsed dendritic cells is dependent on IL-4 or IL-12 production by recipient cells

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12 December 2020

PI3K-mediated negative feedback regulation of IL-12 production in DCs

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12 December 2020

Use of the inhibitory effect of apoptotic cells on dendritic cells for graft survival via T-cell deletion and regulatory T cells

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12 December 2020

GSK-3 mediates differentiation and activation of proinflammatory dendritic cells

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12 December 2020

Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance

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12 December 2020

The effect of sirolimus- or cyclosporine-based immunosuppression effects on T-cell subsets in vivo

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12 December 2020

Early administration of IL-12 suppresses EAE through induction of interferon-gamma

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12 December 2020

Interleukin-12 inhibits murine graft-versus-host disease

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12 December 2020

10.1182/BLOOD-2009-10-251488

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20335217%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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