AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion (Q33932435)

30 July 2017

title

AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion (English)

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30 July 2017

9

Bob Lowenberg

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30 July 2017

James C Mulloy

1

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30 July 2017

Vladimir Jankovic

2

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30 July 2017

Mark Wunderlich

3

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30 July 2017

Ruud Delwel

4

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30 July 2017

Jorg Cammenga

5

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30 July 2017

Ondrej Krejci

6

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30 July 2017

Hui Zhao

7

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30 July 2017

Peter J M Valk

8

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30 July 2017

Stephen D Nimer

10

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30 July 2017

language of work or name

English

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publication date

24 February 2005

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

102

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30 July 2017

issue

11

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30 July 2017

page(s)

4016-4021

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Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

30 July 2017

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AML1-ETO inhibits maturation of multiple lymphohematopoietic lineages and induces myeloblast transformation in synergy with ICSBP deficiency

28 July 2018

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Induction of C/EBPalpha activity alters gene expression and differentiation of human CD34+ cells.

28 July 2018

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Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

28 July 2018

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28 July 2018

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28 July 2018

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AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

28 July 2018

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ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

28 July 2018

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ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

28 July 2018

1 reference

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Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor

28 July 2018

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28 July 2018

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The AML1/ETO fusion protein activates transcription of BCL-2

28 July 2018

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28 July 2018

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28 July 2018

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Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis

28 July 2018

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Nerve growth factor is involved in the supportive effect by bone marrow--derived stromal cells of the factor-dependent human cell line UT-7.

28 July 2018

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The AML1/ETO fusion protein blocks transactivation of the GM-CSF promoter by AML1B.

28 July 2018

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28 July 2018

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The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript

28 July 2018

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28 July 2018

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The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

28 July 2018

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28 July 2018

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Core binding factor and its role in normal hematopoietic development

21 January 2018

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High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia

21 January 2018

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 January 2018

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Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

21 January 2018

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Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

21 January 2018

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The t(8;21) fusion protein, AML1/ETO, transforms NIH3T3 cells and activates AP-1.

21 January 2018

1 reference

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The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0404701102

Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0404701102

Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0404701102

Expression of neurotrophins and their receptors in human bone marrow

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0404701102

Prognostically useful gene-expression profiles in acute myeloid leukemia.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0404701102

An activated receptor tyrosine kinase, TEL/PDGFbetaR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0404701102

Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0404701102

Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554792

Expression of a knocked-in AML1-ETO leukemia gene inhibits the establishment of normal definitive hematopoiesis and directly generates dysplastic hematopoietic progenitors.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554792

Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair

29 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0404701102

Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemias

21 January 2018

1 reference

12 December 2020

Analysis of genes under the downstream control of the t(8;21) fusion protein AML1-MTG8: overexpression of the TIS11b (ERF-1, cMG1) gene induces myeloid cell proliferation in response to G-CSF

1 reference

12 December 2020

High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2 alpha B gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21

1 reference

12 December 2020

Murine leukemia induced by retroviral gene marking

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12 December 2020

Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0404701102

1 reference

30 July 2017

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1 reference

30 July 2017

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