Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register (Q33934705)

30 July 2017

Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register (English)

1 reference

30 July 2017

1 reference

Philippa Marrack

4

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John Kappler

series ordinal

6

object named as

John W Kappler

1 reference

30 July 2017

5

George S Eisenbarth

1 reference

30 July 2017

1

Brian D Stadinski

1 reference

30 July 2017

Li Zhang

2

1 reference

PubMed ID

20534455

30 July 2017

Frances Crawford

series ordinal

3

1 reference

PubMed ID

20534455

30 July 2017

language of work or name

English

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publication date

1 June 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

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30 July 2017

107

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30 July 2017

10978-10983

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30 July 2017

24

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Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Chromogranin A is an autoantigen in type 1 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

New design of MHC class II tetramers to accommodate fundamental principles of antigen presentation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Insulin as an autoantigen in NOD/human diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Disulfide bond engineering to trap peptides in the MHC class I binding groove

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Post-translational modifications of self antigens: implications for autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Peptide register shifting within the MHC groove: theory becomes reality

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Binding interactions between peptides and proteins of the class II major histocompatibility complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Structural and functional consequences of altering a peptide MHC anchor residue

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Production of soluble MHC class II proteins with covalently bound single peptides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890771

In APCs, the autologous peptides selected by the diabetogenic I-Ag7 molecule are unique and determined by the amino acid changes in the P9 pocket

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1006545107

The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1006545107

Peptide 'Velcro': design of a heterodimeric coiled coil.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1006545107

Antigen-specific. I region-restricted interactions in vitro between tumor cell lines and T cell hybridomas

21 January 2018

1 reference

12 December 2020

The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders

1 reference

12 December 2020

Three recessive loci required for insulin-dependent diabetes in nonobese diabetic mice

1 reference

12 December 2020

Dual overlapping peptides recognized by insulin peptide B:9-23 T cell receptor AV13S3 T cell clones of the NOD mouse

1 reference

12 December 2020

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

1 reference

12 December 2020

The insulin-specific T cells of nonobese diabetic mice recognize a weak MHC-binding segment in more than one form

1 reference

12 December 2020

On the pathogenicity of autoantigen-specific T-cell receptors

1 reference

12 December 2020

Self peptides isolated from MHC glycoproteins of non-obese diabetic mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1006545107

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference

PubMed ID

20534455