Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors (Q33935153)

30 July 2017

Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors (English)

1 reference

30 July 2017

1 reference

1 reference

Chitra Subramanian

1

1 reference

30 July 2017

Anthony W Opipari

2

1 reference

30 July 2017

Xin Bian

3

1 reference

30 July 2017

Valerie P Castle

4

1 reference

30 July 2017

Roland P S Kwok

5

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30 July 2017

language of work or name

English

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publication date

18 March 2005

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

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30 July 2017

102

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30 July 2017

13

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30 July 2017

4842-4847

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Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Apoptosis pathways in neuroblastoma therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

The p53 pathway and its inactivation in neuroblastoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Adenovirus-mediated heat-activated antisense Ku70 expression radiosensitizes tumor cells in vitro and in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Histone Deacetylases: Unique Players in Shaping the Epigenetic Histone Code

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Ku70 suppresses the apoptotic translocation of Bax to mitochondria.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Suppression of a DNA double-strand break repair gene, Ku70, increases radio- and chemosensitivity in a human lung carcinoma cell line

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Apoptosomes: engines for caspase activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

MS-27-275, an inhibitor of histone deacetylase, has marked in vitro and in vivo antitumor activity against pediatric solid tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Sensing and repairing DNA double-strand breaks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Histone deacetylases and cancer: causes and therapies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Deacetylase enzymes: biological functions and the use of small-molecule inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

The mitochondrial apoptosome: a killer unleashed by the cytochrome seas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Histone deacetylase inhibitors and retinoic acids inhibit growth of human neuroblastoma in vitro.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Expression of Ku70 correlates with survival in carcinoma of the cervix.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Regulation of gene expression by transcription factor acetylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Review: chromatin structural features and targets that regulate transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Histone deacetylases: silencers for hire.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Mitochondria and apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Death receptors: signaling and modulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408351102

Caspase 3 and 8 deficiency in human neuroblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408351102

NF-kappa B activation mediates doxorubicin-induced cell death in N-type neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408351102

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408351102

Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408351102

Acetylation of p53 inhibits its ubiquitination by Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408351102

Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0408351102

The histone deacetylase inhibitor, CBHA, inhibits growth of human neuroblastoma xenografts in vivo, alone and synergistically with all-trans retinoic acid.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=555706

Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders

29 October 2018

1 reference

12 December 2020

Loss of transcription factor AP-1 DNA binding activity during lymphocyte aging in vivo

1 reference

12 December 2020

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

1 reference

12 December 2020

LMCE3 treatment strategy: results in 99 consecutively diagnosed stage 4 neuroblastomas in children older than 1 year at diagnosis

1 reference

12 December 2020

Biologic factors determine prognosis in infants with stage IV neuroblastoma: A prospective Children's Cancer Group study

1 reference

12 December 2020

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0408351102

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference