hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase (Q24291829)

tumor protein p53

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negative regulation of transcription, DNA-templated

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Sirtuin 1

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author

Robert Weinberg

8

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author name string

H Vaziri

1

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S K Dessain

2

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E Ng Eaton

3

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S I Imai

4

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R A Frye

5

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T K Pandita

6

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L Guarente

Post-translational modification of p53 protein in response to ionizing radiation analyzed by mass spectrometry

7

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language of work or name

English

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publication date

19 October 2001

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published in

Cell

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volume

107

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page(s)

149-59

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issue

2

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cites work

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7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

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7 January 2021

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

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7 January 2021

Inactivation of 14-3-3sigma influences telomere behavior and ionizing radiation-induced chromosomal instability

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

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7 January 2021

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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7 January 2021

Diverse and dynamic functions of the Sir silencing complex

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7 January 2021

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

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7 January 2021

MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900527-X

7 January 2021

Phosphorylation of p53 serine 15 increases interaction with CBP

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7 January 2021

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis

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7 January 2021

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

1 reference

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7 January 2021

Deacetylation of p53 modulates its effect on cell growth and apoptosis

1 reference

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7 January 2021

Negative control of p53 by Sir2alpha promotes cell survival under stress

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7 January 2021

Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast

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7 January 2021

DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p.

1 reference

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7 January 2021

MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks

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7 January 2021

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

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7 January 2021

Regulation of the p53 tumor suppressor protein

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7 January 2021

DNA damage activates p53 through a phosphorylation-acetylation cascade

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7 January 2021

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

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7 January 2021

DNA damage induces phosphorylation of the amino terminus of p53

1 reference

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7 January 2021

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

1 reference

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7 January 2021

An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing

1 reference

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7 January 2021

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

1 reference

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7 January 2021

Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts

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7 January 2021

Surfing the p53 network

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7 January 2021

10.1016/S0092-8674(01)00527-X

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

59795

59795

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference