Is the iron donor lipocalin 2 implicated in the pathophysiology of hereditary hemochromatosis? (Q33935835)

30 July 2017

title

Is the iron donor lipocalin 2 implicated in the pathophysiology of hereditary hemochromatosis? (English)

1 reference

30 July 2017

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Hua Huang

1

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30 July 2017

Shizuo Akira

series ordinal

2

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30 July 2017

Manuela M Santos

series ordinal

3

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30 July 2017

language of work or name

English

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publication date

1 March 2009

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30 July 2017

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30 July 2017

volume

49

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30 July 2017

issue

3

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30 July 2017

page(s)

1012-1016

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Neutrophil gelatinase-associated lipocalin: new paths for an old shuttle.

30 July 2017

cites work

1 reference

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Neutrophil gelatinase-associated lipocalin as the real-time indicator of active kidney damage.

5 July 2018

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Dual action of neutrophil gelatinase-associated lipocalin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells

5 July 2018

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Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation.

5 July 2018

1 reference

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Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver

5 July 2018

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Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury

5 July 2018

1 reference

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Lipocalin 2 diminishes invasiveness and metastasis of Ras-transformed cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake

5 July 2018

1 reference

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Structure-function analysis of a novel member of the LIV-1 subfamily of zinc transporters, ZIP14

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Detection of intracellular iron by its regulatory effect

5 July 2018

1 reference

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Hereditary hemochromatosis--a new look at an old disease

5 July 2018

1 reference

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Mechanisms of cellular iron acquisition: another iron in the fire

5 July 2018

1 reference

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An iron delivery pathway mediated by a lipocalin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

The importance of non-transferrin bound iron in disorders of iron metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Genetic disorders affecting proteins of iron metabolism: clinical implications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

The transferrin receptor: role in health and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

The C282Y mutation causing hereditary hemochromatosis does not produce a null allele

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Characterization of transferrin-independent iron transport in K562 cells. Unique properties provide evidence for multiple pathways of iron uptake.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Efficient clearance of non-transferrin-bound iron by rat liver. Implications for hepatic iron loading in iron overload states

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: a rodent model for hemochromatosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis

5 July 2018

1 reference

Amelioration of ischemic acute renal injury by neutrophil gelatinase-associated lipocalin

21 January 2018

1 reference

Delivery of ferric ion to mouse spermatozoa is mediated by lipocalin internalization.

21 January 2018

1 reference

Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells

21 January 2018

1 reference

Modulation of iron uptake in heart by L-type Ca2+ channel modifiers: possible implications in iron overload.

21 January 2018

1 reference

L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy

21 January 2018

1 reference

Lipocalin 2 functions as a negative regulator of red blood cell production in an autocrine fashion

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891005

Voltage-gated calcium channels provide an alternate route for iron uptake in neuronal cell cultures

10 December 2018

1 reference

12 December 2020

Uptake of non-transferrin-bound iron by both reductive and nonreductive processes is modulated by intracellular iron

1 reference

12 December 2020

Regulation of the transferrin-independent iron transport system in cultured cells

1 reference

12 December 2020

Decreased liver hepcidin expression in the Hfe knockout mouse

1 reference

12 December 2020

Removal of lactoferrin from plasma is mediated by binding to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor and transport to endosomes

1 reference

12 December 2020

Determination of non-transferrin-bound iron in genetic hemochromatosis using a new HPLC-based method

1 reference

12 December 2020

Identifiers

DOI

10.1002/HEP.22699

1 reference

30 July 2017

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30 July 2017

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