Focal adhesion kinase functions as a receptor-proximal signaling component required for directed cell migration (Q33942091)

30 July 2017

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title

Focal adhesion kinase functions as a receptor-proximal signaling component required for directed cell migration (English)

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30 July 2017

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Hauck CR

1

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30 July 2017

Klingbeil CK

series ordinal

2

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30 July 2017

Schlaepfer DD

series ordinal

3

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30 July 2017

publication date

1 January 2000

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30 July 2017

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30 July 2017

volume

21

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30 July 2017

issue

2-3

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30 July 2017

page(s)

293-303

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Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences.

30 July 2017

cites work

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12 December 2020

Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs

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12 December 2020

The interaction of activated integrin lymphocyte function-associated antigen 1 with ligand intercellular adhesion molecule 1 induces activation and redistribution of focal adhesion kinase and proline-rich tyrosine kinase 2 in T lymphocytes.

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12 December 2020

Signaling through focal adhesion kinase

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12 December 2020

Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase

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12 December 2020

p59fyn-p125FAK cooperation in development of CD4+CD8+ thymocytes

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12 December 2020

Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase

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12 December 2020

Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.

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12 December 2020

Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells

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12 December 2020

Direct and rapid induction of migration in human CD4+ T lymphocytes within three-dimensional collagen matrices mediated by signalling via CD3 and/or CD2.

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12 December 2020

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

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12 December 2020

Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

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12 December 2020

Cytoskeletal changes induced by GRAF, the GTPase regulator associated with focal adhesion kinase, are mediated by Rho.

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12 December 2020

Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src

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12 December 2020

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

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12 December 2020

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

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12 December 2020

Proline-rich tyrosine kinase-2 activation by beta 1 integrin fibronectin receptor cross-linking and association with paxillin in human natural killer cells

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12 December 2020

FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line

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12 December 2020

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12 December 2020

Regulation of cell motility by mitogen-activated protein kinase

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12 December 2020

RANTES induces tyrosine kinase activity of stably complexed p125FAK and ZAP-70 in human T cells

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12 December 2020

T cell receptor- and beta 1 integrin-mediated signals synergize to induce tyrosine phosphorylation of focal adhesion kinase (pp125FAK) in human T cells

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12 December 2020

Recent developments in lymphocyte activation: linking kinases to downstream signaling events

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12 December 2020

Differential requirement of protein tyrosine kinases and protein kinase C in the regulation of T cell locomotion in three-dimensional collagen matrices

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12 December 2020

Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

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12 December 2020

Beta1 integrin-mediated activation of focal adhesion kinase and its association with Fyn and Zap-70 in human NK cells

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12 December 2020

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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12 December 2020

Cytotoxic T lymphocytes express a beta3 integrin which can induce the phosphorylation of focal adhesion kinase and the related PYK-2

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12 December 2020

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

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12 December 2020

The N-termini of FAK and JAKs contain divergent band 4.1 domains

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12 December 2020

Adaptors and molecular scaffolds in immune cell signaling

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12 December 2020

Focal adhesion kinase in integrin-mediated signaling

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12 December 2020

Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling

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12 December 2020

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

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12 December 2020

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

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12 December 2020

Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades

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12 December 2020

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

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12 December 2020

FAK integrates growth-factor and integrin signals to promote cell migration

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12 December 2020

The Syk family of protein tyrosine kinases in T-cell activation and development

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12 December 2020

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

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12 December 2020

Integrins: versatility, modulation, and signaling in cell adhesion

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12 December 2020

RAFTK, a novel member of the focal adhesion kinase family, is phosphorylated and associates with signaling molecules upon activation of mature T lymphocytes

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12 December 2020

T cell co-stimulatory molecules other than CD28.

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12 December 2020

Signaling through focal adhesion kinase

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12 December 2020

Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration

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12 December 2020

Focal adhesion kinase: at the crossroads of signal transduction.

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12 December 2020

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

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12 December 2020

Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

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12 December 2020

Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle

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12 December 2020

FAK+ and PYK2/CAKbeta, two related tyrosine kinases highly expressed in the central nervous system: similarities and differences in the expression pattern

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12 December 2020

T cell receptor engagement induces tyrosine phosphorylation of FAK and Pyk2 and their association with Lck.

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12 December 2020

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

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12 December 2020

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

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12 December 2020

Identifiers

DOI

10.1385/IR:21:2-3:293

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Dimensions Publication ID

30 July 2017

1043555687

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