High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis. (Q33944653)

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7 March 2020

title

High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis (English)

1 reference

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7 March 2020

0 references

1 reference

3

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7 March 2020

Charles Mock

5

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7 March 2020

7

Anthony Letai

1 reference

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7 March 2020

author name string

Julia C Liu

1

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7 March 2020

Xiao Guan

2

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7 March 2020

Ana G Rivera

4

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7 March 2020

Vishesh Agrawal

6

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7 March 2020

Paul H Lerou

8

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7 March 2020

Galit Lahav

9

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7 March 2020

language of work or name

English

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publication date

15 August 2013

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7 March 2020

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7 March 2020

volume

13

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7 March 2020

issue

4

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7 March 2020

page(s)

483-491

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Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML

7 March 2020

cites work

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Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis

5 July 2018

1 reference

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Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy

5 July 2018

1 reference

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Dynamics of the transcriptome response of cultured human embryonic stem cells to ionizing radiation exposure

5 July 2018

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DNA damage responses in human induced pluripotent stem cells and embryonic stem cells

5 July 2018

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5 July 2018

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gammaH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization

5 July 2018

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5 July 2018

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Survival responses of human embryonic stem cells to DNA damage

5 July 2018

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ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor

5 July 2018

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Transcriptional control of human p53-regulated genes

5 July 2018

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p53 in health and disease

5 July 2018

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Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

5 July 2018

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PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

5 July 2018

1 reference

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

5 July 2018

1 reference

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

5 July 2018

1 reference

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Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination

5 July 2018

1 reference

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The role of p53 in determining sensitivity to radiotherapy

5 July 2018

1 reference

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A system for stable expression of short interfering RNAs in mammalian cells

5 July 2018

1 reference

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APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis

5 July 2018

1 reference

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PUMA, a novel proapoptotic gene, is induced by p53

5 July 2018

1 reference

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5 July 2018

Surfing the p53 network

1 reference

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p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

5 July 2018

1 reference

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

5 July 2018

1 reference

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Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

5 July 2018

1 reference

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p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

5 July 2018

1 reference

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Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo

5 July 2018

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Induction and repair of DNA damage in normal and ataxiatelangiectasia skin fibroblasts treated with neocarzinostatin

5 July 2018

1 reference

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Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro

5 July 2018

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p53 is required for etoposide-induced apoptosis of human embryonic stem cells

5 July 2018

1 reference

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Differentiation is coupled to changes in the cell cycle regulatory apparatus of human embryonic stem cells

29 October 2018

1 reference

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Regulation of apoptosis and differentiation by p53 in human embryonic stem cells

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23954752

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23954752

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STEM.2013.07.018

1 reference

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7 March 2020

1 reference

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7 March 2020

PubMed publication ID

23954752

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23954752%20AND%20SRC:MED&resulttype=core&format=json