A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes (Q77649645)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11850816%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

title

A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11850816%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

author name string

Edward C Thornborrow

1

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7 December 2019

Sejal Patel

2

1 reference

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7 December 2019

Anthony E Mastropietro

3

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7 December 2019

Elissa M Schwartzfarb

4

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7 December 2019

James J Manfredi

5

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7 December 2019

language of work or name

English

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publication date

1 February 2002

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7 December 2019

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7 December 2019

volume

21

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7 December 2019

issue

7

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7 December 2019

page(s)

990-999

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205069

7 December 2019

exact match

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cites work

Suppression of human colorectal carcinoma cell growth by wild-type p53

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7 January 2021

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

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7 January 2021

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

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7 January 2021

Definition of a consensus binding site for p53

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7 January 2021

Presence of a potent transcription activating sequence in the p53 protein

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7 January 2021

A transcriptionally active DNA-binding site for human p53 protein complexes

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7 January 2021

Molecular cloning and functional analysis of the murine bax gene promoter

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7 January 2021

Bax directly induces release of cytochrome c from isolated mitochondria

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7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

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7 January 2021

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

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7 January 2021

Release of cytochrome c and decrease of cytochrome c oxidase in Bax-expressing yeast cells, and prevention of these effects by coexpression of Bcl-xL

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7 January 2021

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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7 January 2021

The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition

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7 January 2021

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

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7 January 2021

Sequence-specific transcriptional activation is essential for growth suppression by p53.

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7 January 2021

Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53

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7 January 2021

The activity of the murine Bax promoter is regulated by Sp1/3 and E-box binding proteins but not by p53

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7 January 2021

Cytochrome c in the apoptotic and antioxidant cascades

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7 January 2021

One mechanism for cell type-specific regulation of the bax promoter by the tumor suppressor p53 is dictated by the p53 response element

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7 January 2021

The tumor suppressor protein p53 requires a cofactor to activate transcriptionally the human BAX promoter

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7 January 2021

p53 domains: identification and characterization of two autonomous DNA-binding regions.

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7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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7 January 2021

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

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7 January 2021

Role of BAX in the apoptotic response to anticancer agents

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7 January 2021