A role of phosphodiesterase-3B pathway in mediating leptin action on proopiomelanocortin and neurotensin neurons in the hypothalamus (Q33946168)

30 July 2017

title

A role of phosphodiesterase-3B pathway in mediating leptin action on proopiomelanocortin and neurotensin neurons in the hypothalamus (English)

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30 July 2017

Abhiram Sahu

1

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30 July 2017

language of work or name

English

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publication date

13 May 2010

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30 July 2017

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30 July 2017

volume

479

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30 July 2017

issue

1

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30 July 2017

page(s)

18-21

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Effects of chronic central leptin infusion on proopiomelanocortin and neurotensin gene expression in the rat hypothalamus

30 July 2017

cites work

1 reference

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5 July 2018

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Specific physiological roles for signal transducer and activator of transcription 3 in leptin receptor-expressing neurons

5 July 2018

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Anorexigenic hormones leptin, insulin, and alpha-melanocyte-stimulating hormone directly induce neurotensin (NT) gene expression in novel NT-expressing cell models.

5 July 2018

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Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism

5 July 2018

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Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation

5 July 2018

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AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

5 July 2018

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Leptin signaling in the hypothalamus: emphasis on energy homeostasis and leptin resistance

5 July 2018

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STAT3 signalling is required for leptin regulation of energy balance but not reproduction

5 July 2018

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Resistance to the satiety action of leptin following chronic central leptin infusion is associated with the development of leptin resistance in neuropeptide Y neurones

5 July 2018

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A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding

5 July 2018

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Intracellular signalling. Key enzyme in leptin-induced anorexia

5 July 2018

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Selective deletion of leptin receptor in neurons leads to obesity

5 July 2018

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Leptin-induced nuclear translocation of STAT3 immunoreactivity in hypothalamic nuclei involved in body weight regulation.

5 July 2018

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5 July 2018

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Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

5 July 2018

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Activation of downstream signals by the long form of the leptin receptor

5 July 2018

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Central nervous system control of food intake

5 July 2018

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Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area.

5 July 2018

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5 July 2018

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5 July 2018

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Distributions of leptin receptor mRNA isoforms in the rat brain

5 July 2018

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Evidence suggesting that galanin (GAL), melanin-concentrating hormone (MCH), neurotensin (NT), proopiomelanocortin (POMC) and neuropeptide Y (NPY) are targets of leptin signaling in the hypothalamus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Divergent signaling capacities of the long and short isoforms of the leptin receptor

5 July 2018

1 reference

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Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

5 July 2018

1 reference

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5 July 2018

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The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line

5 July 2018

1 reference

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Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

5 July 2018

1 reference

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Defective STAT signaling by the leptin receptor in diabetic mice

5 July 2018

1 reference

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Positional cloning of the mouse obese gene and its human homologue

5 July 2018

1 reference

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The effect of neurotensin on food consumption in the rat.

5 July 2018

1 reference

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The rat gene encoding neurotensin and neuromedin N. Structure, tissue-specific expression, and evolution of exon sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Multiplex solution hybridization-ribonuclease protection assay for quantitation of different ribonucleic Acid transcripts from snap-frozen neuroendocrine tissues of individual animals.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Hypothalamic phosphatidylinositol 3-kinase-phosphodiesterase 3B-cyclic AMP pathway of leptin signalling is impaired following chronic central leptin infusion

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

The anorectic effect of neurotensin is mediated via a histamine H1 receptor in mice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling before obesity onset

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Leptin signaling in the hypothalamus during chronic central leptin infusion

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Role of Signal Transducer and Activator of Transcription 3 in Regulation of Hypothalamic Proopiomelanocortin Gene Expression by Leptin

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Transgenic complementation of leptin-receptor deficiency. I. Rescue of the obesity/diabetes phenotype of LEPR-null mice expressing a LEPR-B transgene

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Divergent roles of SHP-2 in ERK activation by leptin receptors

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Central administration of leptin inhibits food intake and activates the sympathetic nervous system in rhesus macaques

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Neurotensin: effects of hypothalamic and intravenous injections on eating and drinking in rats

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Effect of centrally administered neurotensin on multiple feeding paradigms

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893383

Quantification of NPY mRNA by ribonuclease protection assay

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20471454

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effects of neuropeptide Y, NPY analog (norleucine4-NPY), galanin and neuropeptide K on LH release in ovariectomized (ovx) and ovx estrogen, progesterone-treated rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20471454

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neurotensin Neurons in the Rat Hypothalamus: An Immunocytochemical Study*

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20471454

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEULET.2010.05.018

1 reference

30 July 2017

1 reference

30 July 2017

1 reference