Anorexigenic hormones leptin, insulin, and alpha-melanocyte-stimulating hormone directly induce neurotensin (NT) gene expression in novel NT-expressing cell models. (Q38319973)

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English	Anorexigenic hormones leptin, insulin, and alpha-melanocyte-stimulating hormone directly induce neurotensin (NT) gene expression in novel NT-expressing cell models.	scientific article

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8 January 2020

Anorexigenic hormones leptin, insulin, and alpha-melanocyte-stimulating hormone directly induce neurotensin (NT) gene expression in novel NT-expressing cell models (English)

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8 January 2020

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Hong Cui

1

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8 January 2020

Fang Cai

2

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8 January 2020

Denise D Belsham

3

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1 October 2005

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8 January 2020

Journal of Neuroscience

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8 January 2020

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8 January 2020

9497-9506

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8 January 2020

Leptin receptor long-form splice-variant protein expression in neuron cell bodies of the brain and co-localization with neuropeptide Y mRNA in the arcuate nucleus.

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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From lesions to leptin: hypothalamic control of food intake and body weight.

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Model for the regulation of energy balance and adiposity by the central nervous system

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Leptin sensitive neurons in the hypothalamus

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https://pubmed.ncbi.nlm.nih.gov/16221860

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Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area.

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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The role of SOCS-3 in leptin signaling and leptin resistance

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Activation of downstream signals by the long form of the leptin receptor

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Effect of chronic intraperitoneal injections of leptin on hypothalamic neurotensin content and food intake

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Chemical characterization of leptin-activated neurons in the rat brain

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Neurotensin: peptide for the next millennium

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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Divergent roles of SHP-2 in ERK activation by leptin receptors

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Evidence that neurotensin mediates the central effect of leptin on food intake in rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Pharmacotherapy of obesity: targets and perspectives

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Neurotensin-deficient mice show altered responses to antipsychotic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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The amino acid sequence of a hypothalamic peptide, neurotensin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Genetic approaches to studying energy balance: perception and integration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Neurotensin phase-shifts the firing rate rhythm of neurons in the rat suprachiasmatic nuclei in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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Multiple neural systems controlling food intake and body weight

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Targeted inactivation of the neurotensin type 1 receptor reveals its role in body temperature control and feeding behavior but not in analgesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Opposite regulation of myc and p21waf1 transcription by STAT3 proteins

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Leptin-induced transactivation of NPY gene promoter mediated by JAK1, JAK2 and STAT3 in the neural cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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STAT3 signalling is required for leptin regulation of energy balance but not reproduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities

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https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Cloning of human neurotensin/neuromedin N genomic sequences and expression in the ventral mesencephalon of schizophrenics and age/sex matched controls

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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Hypothalamic neuronal networks and feeding-related peptides involved in the regulation of feeding

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Generation of a Phenotypic Array of Hypothalamic Neuronal Cell Models to Study Complex Neuroendocrine Disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Leptin signaling in the hypothalamus: emphasis on energy homeostasis and leptin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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Region-specific leptin resistance within the hypothalamus of diet-induced obese mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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The STAT3 transcription factor is a target for the Myc and riboblastoma proteins on the Cdc25A promoter.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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A recombinant murine retrovirus for simian virus 40 large T cDNA transforms mouse fibroblasts to anchorage-independent growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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The Isolation of a New Hypotensive Peptide, Neurotensin, from Bovine Hypothalami

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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inferred from PubMed ID database lookup

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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Light and electron microscopic immunocytochemistry of neurotensin-like immunoreactive neurons in the rat hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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Neurotensin: effects of hypothalamic and intravenous injections on eating and drinking in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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Neurotensin Neurons in the Rat Hypothalamus: An Immunocytochemical Study*

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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Synergistic activation of neurotensin/neuromedin N gene expression by c-Jun and glucocorticoids: novel effects of Fos family proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positional cloning of the mouse obese gene and its human homologue

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Identification and expression cloning of a leptin receptor, OB-R

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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inferred from PubMed ID database lookup

NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal splicing of the leptin receptor in diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective STAT signaling by the leptin receptor in diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of leptin in the neuroendocrine response to fasting

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotensin and neuroendocrine regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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Leptin activates PI-3 kinase in C2C12 myotubes via janus kinase-2 (JAK-2) and insulin receptor substrate-2 (IRS-2) dependent pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence suggesting that galanin (GAL), melanin-concentrating hormone (MCH), neurotensin (NT), proopiomelanocortin (POMC) and neuropeptide Y (NPY) are targets of leptin signaling in the hypothalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of gonadotropin-releasing hormone (GnRH) gene expression by 5alpha-dihydrotestosterone in GnRH-secreting GT1-7 hypothalamic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional effects of estrogen on neuronal neurotensin gene expression involve cAMP/protein kinase A-dependent signaling mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

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The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin signaling in the hypothalamus of normal rats in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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Evidence that hypothalamic neurotensin signals leptin effects on feeding behavior in normal and fat-preferring rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16221860

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2269-05.2005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221860%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221860%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221860%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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