Inhibition of mTORC1 signaling reduces tumor growth but does not prevent cancer progression in a mouse model of thyroid cancer. (Q33947770)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20299527%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Inhibition of mTORC1 signaling reduces tumor growth but does not prevent cancer progression in a mouse model of thyroid cancer (English)

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21 January 2020

1

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author name string

Laura Fozzatti

2

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21 January 2020

Changxue Lu

3

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21 January 2020

Mark C Willingham

4

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21 January 2020

Sheue-Yann Cheng

5

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21 January 2020

language of work or name

English

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publication date

18 March 2010

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21 January 2020

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21 January 2020

volume

31

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issue

7

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21 January 2020

page(s)

1284-1291

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describes a project that uses

21 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2893796/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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PTEN deficiency accelerates tumour progression in a mouse model of thyroid cancer

5 July 2018

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PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR

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Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.

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Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression

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A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation.

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mTOR and cancer: insights into a complex relationship

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Future directions in the treatment of hormone-sensitive advanced breast cancer: the RAD001 (Everolimus)-letrozole clinical program

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mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

5 July 2018

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Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone beta receptor

5 July 2018

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The TOR pathway: a target for cancer therapy

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Resistance to thyroid hormone

5 July 2018

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Nitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231): potential role of cyclin D1

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Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone

5 July 2018

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5 July 2018

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A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995 [see commetns]

5 July 2018

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Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

5 July 2018

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5 July 2018

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5 July 2018

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Mammalian target of rapamycin is the key effector of phosphatidylinositol-3-OH-initiated proliferative signals in the thyroid follicular epithelium

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Inhibition of phosphatidylinositol 3-kinase delays tumor progression and blocks metastatic spread in a mouse model of thyroid cancer.

29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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12 December 2020

AKT activation promotes metastasis in a mouse model of follicular thyroid carcinoma

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12 December 2020

The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas

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12 December 2020

Overexpression and overactivation of Akt in thyroid carcinoma

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12 December 2020

Mutant thyroid hormone receptor beta represses the expression and transcriptional activity of peroxisome proliferator-activated receptor gamma during thyroid carcinogenesis

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1093/CARCIN/BGQ059

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20299527%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20299527%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference