'Accidental' anti-angiogenic drugs. anti-oncogene directed signal transduction inhibitors and conventional chemotherapeutic agents as examples (Q33959693)

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English	'Accidental' anti-angiogenic drugs. anti-oncogene directed signal transduction inhibitors and conventional chemotherapeutic agents as examples	scientific article

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scholarly article

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Europe PubMed Central

30 July 2017

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Europe PubMed Central

'Accidental' anti-angiogenic drugs. anti-oncogene directed signal transduction inhibitors and conventional chemotherapeutic agents as examples (English)

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Europe PubMed Central

30 July 2017

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inferred from title

angiogenesis inhibitor

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author name string

Kerbel RS

1

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Europe PubMed Central

30 July 2017

Viloria-Petit A

2

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Europe PubMed Central

30 July 2017

Klement G

3

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Europe PubMed Central

30 July 2017

Rak J

4

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Europe PubMed Central

30 July 2017

publication date

1 June 2000

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Europe PubMed Central

30 July 2017

European Journal of Cancer

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Europe PubMed Central

30 July 2017

36

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Europe PubMed Central

30 July 2017

10

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Europe PubMed Central

30 July 2017

1248-1257

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Europe PubMed Central

30 July 2017

Tumor angiogenesis: past, present and the near future

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7 January 2021

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Anti-angiogenesis: new concept for therapy of solid tumors

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https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Clinical applications of angiogenic growth factors and their inhibitors

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https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy

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https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth

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7 January 2021

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Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance.

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7 January 2021

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Antiangiogenic therapy of a recurrent giant cell tumor of the mandible with interferon alfa-2a.

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7 January 2021

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Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

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7 January 2021

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Combined effects of angiostatin and ionizing radiation in antitumour therapy.

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Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

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7 January 2021

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Review article: angiogenesis, neovascular proliferation and vascular pathophysiology as targets for cancer therapy

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7 January 2021

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Endothelial cell proliferation as a novel approach to targeting tumour therapy

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7 January 2021

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Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: evidence for a vascular mechanism

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Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularization by low-dose methotrexate

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Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

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Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor

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7 January 2021

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Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

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7 January 2021

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Consolidation chemoradiotherapy and autologous bone marrow transplantation versus continued chemotherapy for metastatic neuroblastoma: a report of two concurrent Children's Cancer Group studies

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7 January 2021

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Preclinical studies of the combination of angiogenic inhibitors with cytotoxic agents

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7 January 2021

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Responsiveness of human lung cancer/nude mouse to antitumor agents in a model using clinically equivalent doses

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7 January 2021

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Evaluation of antitumor activity in a human breast tumor/nude mouse model with a special emphasis on treatment dose

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7 January 2021

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Antiangiogenic potential of camptothecin and topotecan

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Phase I trial of docetaxel administered by weekly infusion in patients with advanced refractory cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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A genetic model for colorectal tumorigenesis

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7 January 2021

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Bcl-2 and the regulation of programmed cell death

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https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Bcl-2 blocks p53-dependent apoptosis

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https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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p53-dependent apoptosis suppresses tumor growth and progression in vivo

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https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Apoptosis. Its significance in cancer and cancer therapy

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7 January 2021

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Programmed cell death: apoptosis and oncogenesis.

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7 January 2021

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How tumors become angiogenic

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7 January 2021

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Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

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https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

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7 January 2021

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Angiogenic factors

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7 January 2021

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Vascular endothelial growth factor, a potent and selective angiogenic agent

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https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

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7 January 2021

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Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells.

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7 January 2021

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Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

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7 January 2021

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Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

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https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

1 reference

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7 January 2021

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Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: suppression by mutant c-H-ras oncogene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells

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7 January 2021

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Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Impact of oncogenes in tumor angiogenesis: mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity

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https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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The angiogenic switch in hamster buccal pouch keratinocytes is dependent on TGFbeta-1 and is unaffected by ras activation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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VEGF mRNA is stabilized by ras and tyrosine kinase oncogenes, as well as by UV radiation--evidence for divergent stabilization pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Effect of novel CAAX peptidomimetic farnesyltransferase inhibitor on angiogenesis in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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c-fos is required for malignant progression of skin tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Oncogenes and tumor angiogenesis: the HPV-16 E6 oncoprotein activates the vascular endothelial growth factor (VEGF) gene promoter in a p53 independent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

based on heuristic

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Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

based on heuristic

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Repression of thrombospondin-1 expression, a natural inhibitor of angiogenesis, in polyoma middle T transformed NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

based on heuristic

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Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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Additional corrections: interferon for hemangiomas of infancy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Interferon alfa-2a therapy for life-threatening hemangiomas of infancy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

based on heuristic

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The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

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[Inhibition of tumor neo-angiogenesis and induction of apoptosis as properties of docetaxel (taxotere)]

1 reference

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7 January 2021

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Inhibition of angiogenesis by anthracyclines and titanocene dichloride.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Angiogenesis induced by urothelial cells (HCV-29) and their v-ras and v-raf transfectants

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative expression of novel vascular endothelial growth factor/vascular permeability factor transcripts in skin, papillomas, and carcinomas of v-Ha-ras Tg.AC transgenic mice and FVB/N mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Lovastatin and tumor necrosis factor-alpha exhibit potentiated antitumor effects against Ha-ras-transformed murine tumor via inhibition of tumor-induced angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2800%2900092-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Essential role for oncogenic Ras in tumour maintenance

1 reference

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7 January 2021

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Identifiers

10.1016/S0959-8049(00)00092-7

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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