Functional expression and localization of P-glycoprotein at the blood brain barrier (Q33960099)

30 July 2017

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title

Functional expression and localization of P-glycoprotein at the blood brain barrier (English)

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30 July 2017

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Reina Bendayan

1

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PubMed ID

12112443

30 July 2017

Gloria Lee

series ordinal

2

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PubMed ID

12112443

30 July 2017

Moise Bendayan

series ordinal

3

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30 July 2017

1 June 2002

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Microscopy Research and Technique

30 July 2017

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30 July 2017

57

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30 July 2017

5

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30 July 2017

365-380

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Transporting therapeutics across the blood-brain barrier

30 July 2017

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Differential modulation of P-glycoprotein transport by protein kinase inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Polarity of the Blood-Brain Barrier: Neutral Amino Acid Transport into Isolated Brain Capillaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Isolated Brain Microvessels: A Purified, Metabolically Active Preparation from Bovine Cerebral Cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Transcytosis of macromolecules through the blood-brain barrier: a cell biological perspective and critical appraisal

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Independent blood-brain barrier transport systems for nucleic acid precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Functional expression of P-glycoprotein and multidrug resistance-associated protein (Mrp1) in primary cultures of rat astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Transport properties of P-glycoprotein in plasma membrane vesicles from multidrug-resistant Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Detection of P glycoprotein activity on normal and leukemic CD34+ cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Nitric oxide and endothelin secretion by brain microvessel endothelial cells: regulation by cyclic nucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

The P-glycoprotein multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Expression of a multidrug-resistance gene in human tumors and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

P-Glycoprotein on astrocyte foot processes of unfixed isolated human brain capillaries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Isolation of metabolically active capillaries from rat brain1,2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Biochemistry of multidrug resistance mediated by the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Isolation and expression of a complementary DNA that confers multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

A comparative study on the uptake and subsequent decarboxylation of monoamine precursors in cerebral microvessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Is the multidrug transporter a flippase?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

mRna expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Characterization of transferrin receptor in an immortalized cell line of rat brain endothelial cells, RBE4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

High levels of P-glycoprotein detected in isolated brain capillaries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Cerebral and pial microvessels: differential expression of gamma-glutamyl transpeptidase and alkaline phosphatase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Neurotrophic and neuroprotective actions of estrogens and their therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Role of P-glycoprotein in the renal transport of dideoxynucleoside analog drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Multidrug resistance: molecular mechanisms and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Reduced permeability in CHO cells as a mechanism of resistance to colchicine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Phosphorylation of the multidrug resistance associated glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Bovine brain endothelial cells express tight junctions and monoamine oxidase activity in long-term culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

The Susceptibility of Cerebral Endothelial Cells to Astroglial Induction of Blood-Brain Barrier Enzymes Depends on Their Proliferative State

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Potential mechanisms of the age-related changes in the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Isolation of brain capillaries: a simplified technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Monoclonal antibodies specific for P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Fine structural localization of a blood-brain barrier to exogenous peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Glucose transport in immortalized rat brain capillary endothelial cells in vitro: transport activity and GLUT1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Multidrug resistance: molecular biology and clinical relevance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Phosphatidylcholine translocase: a physiological role for the mdr2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Barrier mechanisms in the brain, I. Adult brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

The physiological function of drug-transporting P-glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Functional intracellular P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

The P-glycoprotein efflux pump: how does it transport drugs?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Induction of blood-brain barrier properties in immortalized bovine brain endothelial cells by astrocytic factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Morphological and functional characterization of an in vitro blood-brain barrier model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Specialized localization of P-glycoprotein recognized by MRK 16 monoclonal antibody in endothelial cells of the brain and the spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Conditionally immortalized cell lines as a new in vitro model for the study of barrier functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Mapping of phenytoin-inducible cytochrome P450 immunoreactivity in the mouse central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

P-glycoprotein is localized in caveolae in resistant cells and in brain capillaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.10090

21 January 2018

Identifiers

DOI

10.1002/JEMT.10090

1 reference

30 July 2017

1 reference

PubMed ID

12112443