NOD mice are defective in proteasome production and activation of NF-kappaB (Q33961022)

30 July 2017

title

NOD mice are defective in proteasome production and activation of NF-kappaB (English)

1 reference

30 July 2017

1 reference

T Hayashi

1

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30 July 2017

D Faustman

series ordinal

2

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30 July 2017

language of work or name

English

0 references

publication date

1 December 1999

1 reference

Molecular and Cellular Biology

30 July 2017

published in

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30 July 2017

volume

19

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30 July 2017

issue

12

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30 July 2017

page(s)

8646-8659

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The NOD mouse model of type 1 diabetes: as good as it gets?

30 July 2017

cites work

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Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

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TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

5 July 2018

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Inhibition of NF-kappaB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis.

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5 July 2018

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5 July 2018

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Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome

5 July 2018

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5 July 2018

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5 July 2018

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Requirement for NF-kappaB in osteoclast and B-cell development

5 July 2018

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5 July 2018

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IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

5 July 2018

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IkappaB kinase: beginning, not the end

5 July 2018

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Developmental regulation of MHC class II transport in mouse dendritic cells.

5 July 2018

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Proteasome subunits, low-molecular-mass polypeptides 2 and 7 are hyperexpressed by target cells in autoimmune thyroid disease but not in insulin-dependent diabetes mellitus: implications for autoimmunity

5 July 2018

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

5 July 2018

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Identification and characterization of an IkappaB kinase

5 July 2018

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Protection of NIT-1 pancreatic beta-cells from immune attack by inhibition of NF-kappaB.

5 July 2018

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Proteasome regulation of activation-induced T cell death

5 July 2018

1 reference

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Interleukin-1 beta inhibits rat thyroid cell function in vivo and in vitro by an NO-independent mechanism and induces hypothyroidism and accelerated thyroiditis in diabetes-prone BB rats

5 July 2018

1 reference

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Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells

5 July 2018

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

5 July 2018

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

5 July 2018

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

5 July 2018

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NF-kappa B: ten years after

5 July 2018

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Structure and functions of the 20S and 26S proteasomes

5 July 2018

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Control of gene expression by proteolysis

5 July 2018

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Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma

5 July 2018

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Proteasome subunits X and Y alter peptidase activities in opposite ways to the interferon-gamma-induced subunits LMP2 and LMP7.

5 July 2018

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Expression of transporter associated with antigen processing-1 in the endocrine cells of human pancreatic islets: effect of cytokines and evidence of hyperexpression in IDDM.

5 July 2018

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Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-kappaB.

5 July 2018

1 reference

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Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin

5 July 2018

1 reference

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Defective major histocompatibility complex class I expression on lymphoid cells in autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85003

Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85003

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85003

cDNA cloning and interferon gamma down-regulation of proteasomal subunits X and Y

5 July 2018

1 reference

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Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

5 July 2018

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Abnormal class I assembly and peptide presentation in the nonobese diabetic mouse

5 July 2018

1 reference

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Activation of NF-kappa B in vivo is regulated by multiple phosphorylations

5 July 2018

1 reference

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Genomic organization of the mouse Lmp-2 gene and characteristic structure of its promoter

5 July 2018

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NF-kappa B: a lesson in family values

5 July 2018

1 reference

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Expression of relB is required for the development of thymic medulla and dendritic cells

5 July 2018

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Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

5 July 2018

1 reference

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Proteasome components with reciprocal expression to that of the MHC-encoded LMP proteins

5 July 2018

1 reference

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Functions of the proteasome: the lysis at the end of the tunnel

5 July 2018

1 reference

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Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation

5 July 2018

1 reference

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

5 July 2018

1 reference

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Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

5 July 2018

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Breeding of a non-obese, diabetic strain of mice

5 July 2018

1 reference

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C. L. Oakley lecture (1987). The pathogenesis of beta cell destruction in type I (insulin-dependent) diabetes mellitus

5 July 2018

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Identification of T cell subsets and class I and class II antigen expression in islet grafts and pancreatic islets of diabetic BioBreeding/Worcester rats

5 July 2018

1 reference

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IDDM in BB rats. Enhanced MHC class I heavy-chain gene expression in pancreatic islets.

5 July 2018

1 reference

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Functionally distinct NF-kappa B binding sites in the immunoglobulin kappa and IL-2 receptor alpha chain genes

5 July 2018

1 reference

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Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B

5 July 2018

1 reference

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Generation of p50 subunit of NF-kappa B by processing of p105 through an ATP-dependent pathway.

5 July 2018

1 reference

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Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85003

B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85003

Overexpression of class I major histocompatibility complex accompanies insulitis in the non-obese diabetic mouse and is prevented by anti-interferon-gamma antibody

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85003

Autoimmune diabetes mellitus in the BB rat

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85003

Kappa B site-dependent activation of the interleukin-2 receptor alpha-chain gene promoter by human c-Rel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85003

Alternative exon usage and processing of the major histocompatibility complex-encoded proteasome subunits

5 July 2018

1 reference

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Role of Rel/NF-kappaB transcription factors during the outgrowth of the vertebrate limb.

5 July 2018

1 reference

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Reduced expression of Tap1 and Lmp2 antigen-processing genes in the nonobese diabetic (NOD) mouse due to a mutation in their shared bidirectional promoter.

29 October 2018

1 reference

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Increase in simultaneous coexpression of naive and memory lymphocyte markers at diagnosis of IDDM.

29 October 2018

1 reference

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Role of CD4+CD45RA+ T cells in the development of autoimmune diabetes in the non-obese diabetic (NOD) mouse.

29 October 2018

1 reference

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Occult CD45 T cell developmental defect in type 1 diabetes.

29 October 2018

1 reference

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Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

29 October 2018

1 reference

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Reduced expression of peptide‐loaded HLA class I molecules on multiple sclerosis lymphocytes

29 October 2018

1 reference

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Altered peptidase and viral-specific T cell response in LMP2 mutant mice.

29 October 2018

1 reference

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Examination of islets in the pancreas biopsy specimens from newly diagnosed Type 1 (insulin-dependent) diabetic patients

29 October 2018

1 reference

12 December 2020

CD5+ B lymphocytes in high-risk islet cell antibody-positive and newly diagnosed IDDM subjects

1 reference

12 December 2020

Linkage of Faulty Major Histocompatibility Complex Class I to Autoimmune Diabetes

1 reference

12 December 2020

Use of donor beta 2-microglobulin-deficient transgenic mouse liver cells for isografts, allografts, and xenografts

1 reference

12 December 2020

Identification of a new serine kinase that activates NF kappa B by direct phosphorylation

1 reference

12 December 2020

NF-κB p105 Processing via the Ubiquitin-Proteasome Pathway

1 reference

12 December 2020

Rejection of allogeneic and syngeneic but not MHC class I-deficient tumor grafts by MHC class I-deficient mice

1 reference

12 December 2020

Antigen processing and autoimmunity. Evaluation of mRNA abundance and function of HLA-linked genes

1 reference

12 December 2020

The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV

1 reference

12 December 2020

Abnormal T-lymphocyte subsets in type I diabetes

1 reference

12 December 2020

Tolerance to peripheral tissue is transient and maintained by tissue-specific class I expression

1 reference

12 December 2020

Defective maturation and function of antigen-presenting cells in type 1 diabetes

1 reference

12 December 2020

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

1 reference

12 December 2020

B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching

1 reference

12 December 2020

Failure of lymphopoiesis after adoptive transfer of NF-kappaB-deficient fetal liver cells

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.19.12.8646

1 reference

30 July 2017

1 reference

30 July 2017

1 reference