Control of gene expression by proteolysis (Q41066929)

26 September 2017

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title

Control of gene expression by proteolysis (English)

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26 September 2017

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2

P A Baeuerle

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26 September 2017

1

H L Pahl

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26 September 2017

1 June 1996

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Current Opinion in Cell Biology

26 September 2017

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26 September 2017

8

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26 September 2017

340-347

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26 September 2017

3

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The regulation of transcription by phosphorylation

26 September 2017

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Proteasomes: protein degradation machines of the cell

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Cyclin ubiquitination: the destructive end of mitosis

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Functions of the proteasome: the lysis at the end of the tunnel

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Ubiquitin, proteasomes, and the regulation of intracellular protein degradation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

The ubiquitin-proteasome proteolytic pathway

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Proteasome from Thermoplasma acidophilum: a threonine protease

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

A new inhibitor of the chymotrypsin-like activity of the multicatalytic proteinase complex (20S proteasome) induces accumulation of ubiquitin-protein conjugates in a neuronal cell.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Suppression of human colorectal carcinoma cell growth by wild-type p53

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Wild-type p53 can inhibit oncogene-mediated focus formation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

The p53 proto-oncogene can act as a suppressor of transformation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

p53 mutations in human cancers

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

The p53 tumour suppressor gene

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Reconstitution of p53-ubiquitinylation reactions from purified components: the role of human ubiquitin-conjugating enzyme UBC4 and E6-associated protein (E6AP)

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Ubiquitinylation is not an absolute requirement for degradation of c-Jun protein by the 26 S proteasome

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Function and activation of NF-kappa B in the immune system

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Generation of p50 subunit of NF-kappa B by processing of p105 through an ATP-dependent pathway.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

NF-kappa B and related proteins: Rel/dorsal homologies meet ankyrin-like repeats

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

In vitro activation and nuclear translocation of NF-kappa B catalyzed by cyclic AMP-dependent protein kinase and protein kinase C.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

The proteasome pathway is required for cytokine-induced endothelial-leukocyte adhesion molecule expression

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Appearance of apparently ubiquitin-conjugated I kappa B-alpha during its phosphorylation-induced degradation in intact cells

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Inducible degradation of I kappa B alpha in vitro and in vivo requires the acidic C-terminal domain of the protein

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

The precursor of NF-kappa B p50 has I kappa B-like functions

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Cactus protein degradation mediates Drosophila dorsal-ventral signaling

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

The role of Notch in lateral inhibition and cell fate specification

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

1 reference

7 January 2021

Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Signalling downstream of activated mammalian Notch

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

A receptor-mediated pathway for cholesterol homeostasis

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

Degradation of the yeast MAT alpha 2 transcriptional regulator is mediated by the proteasome

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https://api.crossref.org/works/10.1016%2FS0955-0674%2896%2980007-X

7 January 2021

10.1016/S0955-0674(96)80007-X

Identifiers

DOI

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26 September 2017

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PubMed ID

8743884