Leptin: a multifunctional hormone (Q33969414)

30 July 2017

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title

Leptin: a multifunctional hormone (English)

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30 July 2017

L Huang

1

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PubMed ID

10896170

30 July 2017

C Li

series ordinal

2

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30 July 2017

1 June 2000

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30 July 2017

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30 July 2017

10

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30 July 2017

81-92

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30 July 2017

2

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https://scigraph.springernature.com/pub.10.1038/sj.cr.7290038

30 July 2017

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cites work

Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Abnormal splicing of the leptin receptor in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Defective STAT signaling by the leptin receptor in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Physiological response to long-term peripheral and central leptin infusion in lean and obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Rapid increase in circulating leptin in ventromedial hypothalamus-lesioned rats: role of hyperinsulinemia and implication for upregulation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

STATs and gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin action in intestinal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Biological action of leptin as an angiogenic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Modulation of insulin activities by leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin receptor action in hepatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Direct effects of leptin on brown and white adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin receptors expressed on pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin signalling in pancreatic islets and clonal insulin-secreting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin receptor missense mutation in the fatty Zucker rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Substitution at codon 269 (glutamine --> proline) of the leptin receptor (OB-R) cDNA is the only mutation found in the Zucker fatty (fa/fa) rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Altered cell surface expression and signaling of leptin receptors containing the fatty mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

OB-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Regulation of fatty acid homeostasis in cells: novel role of leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

A short form of leptin receptor performs signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin receptor signal transduction: OBRa and OBRb of fa type

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Divergent signaling capacities of the long and short isoforms of the leptin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin actions on food intake and body temperature are mediated by IL-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

A leptin missense mutation associated with hypogonadism and morbid obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Congenital leptin deficiency is associated with severe early-onset obesity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

Obesity as a medical problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

7 January 2021

Central nervous system control of food intake

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

7 January 2021

Obesity in the new millennium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

7 January 2021

Leptin promotes aggregation of human platelets via the long form of its receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

7 January 2021

Novel form of lipolysis induced by leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

7 January 2021

Early onset of reproductive function in normal female mice treated with leptin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290038

7 January 2021

Identifiers

DOI

10.1038/SJ.CR.7290038

1 reference

30 July 2017

1 reference

PubMed ID

10896170