Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression (Q36266492)

13 August 2017

Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression (English)

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13 August 2017

M Shimabukuro

1

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13 August 2017

M Y Wang

2

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13 August 2017

Y T Zhou

3

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13 August 2017

C B Newgard

4

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13 August 2017

R H Unger

5

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13 August 2017

language of work or name

English

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publication date

1 August 1998

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Proceedings of the National Academy of Sciences of the United States of America

13 August 2017

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13 August 2017

95

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13 August 2017

16

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13 August 2017

9558-9561

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Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

OB-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Role of nitric oxide in obesity-induced beta cell disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Direct antidiabetic effect of leptin through triglyceride depletion of tissues.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Leptin: the tale of an obesity gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Substitution at codon 269 (glutamine --> proline) of the leptin receptor (OB-R) cDNA is the only mutation found in the Zucker fatty (fa/fa) rat.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Bcl-2 and the regulation of programmed cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Apoptosis in the pathogenesis and treatment of disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Cell death signal transduction and Bcl-2 function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

The proto-oncogene Bcl-2 and its role in regulating apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Leptin receptor missense mutation in the fatty Zucker rat.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Caloric restriction in obese pre-diabetic rats prevents beta-cell depletion, loss of beta-cell GLUT 2 and glucose incompetence

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21377

Bcl-2 antagonizes apoptotic cell death induced by two new ceramide analogues.

29 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9558

Preliminary characterization of calcium binding in islet-cell plasma membranes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9558

Standardization of insulin secretion from pancreatic islets: validation of a DNA assay

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9558

21 January 2018

Identifiers

DOI

10.1073/PNAS.95.16.9558

1 reference

13 August 2017

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1 reference

13 August 2017

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