Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion. (Q33972212)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25009184%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion (English)

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9 March 2020

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8

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9 March 2020

Wei-Guo Zhu

17

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9 March 2020

author name string

Ping Zhang

1

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9 March 2020

Bo Tu

2

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9 March 2020

Hua Wang

3

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9 March 2020

Ziyang Cao

4

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9 March 2020

Ming Tang

5

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9 March 2020

Chaohua Zhang

6

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9 March 2020

Bo Gu

7

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9 March 2020

Lina Wang

9

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9 March 2020

Yang Yang

10

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9 March 2020

Ying Zhao

11

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9 March 2020

Haiying Wang

12

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9 March 2020

Jianyuan Luo

13

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9 March 2020

Chu-Xia Deng

14

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9 March 2020

Bin Gao

15

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9 March 2020

Robert G Roeder

16

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9 March 2020

language of work or name

English

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publication date

9 July 2014

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Proceedings of the National Academy of Sciences of the United States of America

9 March 2020

published in

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9 March 2020

volume

111

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9 March 2020

page(s)

10684-10689

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9 March 2020

issue

29

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p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene

9 March 2020

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1 reference

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5 July 2018

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5 July 2018

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5 July 2018

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Applications of post-translational modifications of FoxO family proteins in biological functions

5 July 2018

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p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

5 July 2018

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5 July 2018

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SIRT6 deficiency results in severe hypoglycemia by enhancing both basal and insulin-stimulated glucose uptake in mice

5 July 2018

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Human SIRT6 promotes DNA end resection through CtIP deacetylation

5 July 2018

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Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis

5 July 2018

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Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

5 July 2018

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SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair

5 July 2018

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The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

5 July 2018

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Blinded by the Light: The Growing Complexity of p53

5 July 2018

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A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

5 July 2018

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Gluconeogenesis: re-evaluating the FOXO1-PGC-1alpha connection

5 July 2018

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TIGAR, a p53-inducible regulator of glycolysis and apoptosis

5 July 2018

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Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

5 July 2018

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FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

5 July 2018

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The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression

5 July 2018

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Mammalian SIRT1 represses forkhead transcription factors

5 July 2018

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5 July 2018

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The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

5 July 2018

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5 July 2018

Surfing the p53 network

1 reference

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Direct control of the Forkhead transcription factor AFX by protein kinase B

5 July 2018

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Identification of p53 as a sequence-specific DNA-binding protein

5 July 2018

1 reference

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p53 promotes the expression of gluconeogenesis-related genes and enhances hepatic glucose production

5 July 2018

1 reference

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Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis

29 October 2018

1 reference

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Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt.

29 October 2018

1 reference

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p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115576

Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver.

29 October 2018

1 reference

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29 October 2018

Identifiers

DOI

10.1073/PNAS.1411026111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25009184%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25009184%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

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