Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus (Q33976323)

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English	Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus	scientific article

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scholarly article

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5 December 2019

Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus (English)

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5 December 2019

Streptomyces clavuligerus

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1 reference

clavulanic acid

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author name string

R H Mosher

1

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5 December 2019

A S Paradkar

2

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5 December 2019

C Anders

3

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B Barton

4

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5 December 2019

S E Jensen

5

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1 May 1999

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5 December 2019

full work available at URL

https://aac.asm.org/content/aac/43/5/1215.full.pdf

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19 March 2024

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Antimicrobial Agents and Chemotherapy

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43

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5

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5 December 2019

1215-1224

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online access status

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access restriction status

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beta-Lactam synthetase: a new biosynthetic enzyme

1 reference

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Purification and characterization of clavaminate synthase from Streptomyces antibioticus. A multifunctional enzyme of clavam biosynthesis

1 reference

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5 July 2018

Functional analysis of the gene encoding the clavaminate synthase 2 isoenzyme involved in clavulanic acid biosynthesis in Streptomyces clavuligerus

1 reference

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Identification, cloning, sequencing, and overexpression of the gene encoding proclavaminate amidino hydrolase and characterization of protein function in clavulanic acid biosynthesis

1 reference

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5 July 2018

Ro 22-5417, a new clavam antibiotic from Streptomyces clavuligerus. I. Discovery and biological activity

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N-Methyl transferase of Streptomyces erythraeus that confers resistance to the macrolide-lincosamide-streptogramin B antibiotics: amino acid sequence and its homology to cognate R-factor enzymes from pathogenic bacilli and cocci.

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Clavamycins, new clavam antibiotics from two variants of Streptomyces hygroscopicus. I. Taxonomy of the producing organisms, fermentation, and biological activities

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Construction and characterisation of a series of multi-copy promoter-probe plasmid vectors for Streptomyces using the aminoglycoside phosphotransferase gene from Tn5 as indicator.

1 reference

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5 July 2018

Two isozymes of clavaminate synthase central to clavulanic acid formation: cloning and sequencing of both genes from Streptomyces clavuligerus

1 reference

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1 reference

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1 reference

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Studies on the biosynthesis of clavulanic acid. III. Incorporation of DL-[3,4-13C2]glutamic acid

1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

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Clavamycins, new clavam antibiotics from two variants of Streptomyces hygroscopicus. I. Taxonomy of the producing organisms, fermentation, and biological activities.

1 reference

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Identifiers

10.1128/AAC.43.5.1215

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5 December 2019

1 reference

Europe PubMed Central

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5 December 2019

1 reference

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5 December 2019

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