Role of AIF in caspase-dependent and caspase-independent cell death (Q33977411)

30 July 2017

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title

Role of AIF in caspase-dependent and caspase-independent cell death (English)

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30 July 2017

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2

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30 July 2017

Sean P Cregan

1

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30 July 2017

Ruth S Slack

series ordinal

3

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30 July 2017

language of work or name

English

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publication date

1 April 2004

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30 July 2017

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30 July 2017

23

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30 July 2017

2785-2796

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30 July 2017

16

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207517

30 July 2017

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cites work

Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Cyclosporin A inhibits caspase-independent death of NGF-deprived sympathetic neurons: a potential role for mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Alternating metabolic pathways in NGF-deprived sympathetic neurons affect caspase-independent death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Glutamate neurotoxicity and diseases of the nervous system

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Mechanisms of NO neurotoxicity.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Apoptosis and karyogamy in syncytia induced by the HIV-1-envelope glycoprotein complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Death commitment point is advanced by axotomy in sympathetic neurons

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Regulated targeting of BAX to mitochondria.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Mitochondrial release of apoptosis-inducing factor and cytochrome c during smooth muscle cell apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Bcl-2 increases emptying of endoplasmic reticulum Ca2+ stores during photodynamic therapy-induced apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Calcium influx through receptor-operated channel induces mitochondria-triggered paraptotic cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Role of apoptosis-inducing factor in myocardial cell death by ischemia-reperfusion.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

The harlequin mouse mutation downregulates apoptosis-inducing factor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Molecular and biochemical features of poly (ADP-ribose) metabolism

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Four deaths and a funeral: from caspases to alternative mechanisms.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Apoptosis in the absence of poly-(ADP-ribose) polymerase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Endonuclease G is an apoptotic DNase when released from mitochondria

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

NADH oxidase activity of mitochondrial apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Possible contribution of apoptosis-inducing factor (AIF) and reactive oxygen species (ROS) to UVB-induced caspase-independent cell death in the T cell line Jurkat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Mitochondria: releasing power for life and unleashing the machineries of death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Cytochrome c release from mitochondria proceeds by a two-step process

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Mitochondria: regulating the inevitable.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Poly (ADP-ribose) polymerase, nitric oxide and cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Dynamic regulation of neuronal NO synthase transcription by calcium influx through a CREB family transcription factor-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Molecular mechanisms of calcium-dependent excitotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Post-mortem high affinity glutamate uptake in human brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Apoptosis and melanoma chemoresistance

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Two distinct pathways leading to nuclear apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Mitochondrial release of caspase-2 and -9 during the apoptotic process

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Measurement of nitric oxide and peroxynitrite generation in the postischemic heart. Evidence for peroxynitrite-mediated reperfusion injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

DNA binding is required for the apoptogenic action of apoptosis inducing factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207517

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207517

1 reference

Dimensions Publication ID

30 July 2017

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1 reference