Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes (Q33980095)

30 July 2017

Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes (English)

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30 July 2017

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Michael Menconi

1

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30 July 2017

Patricia Gonnella

2

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30 July 2017

Victoria Petkova

3

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30 July 2017

Stewart Lecker

4

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30 July 2017

Per-Olof Hasselgren

5

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30 July 2017

1 October 2008

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Journal of Cellular Biochemistry

30 July 2017

1 reference

30 July 2017

105

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30 July 2017

2

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30 July 2017

353-364

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describes a project that uses

30 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2901105/fullTextXML

inferred from PubMed Central ID database lookup

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Glucocorticoids and serotonin alter glucocorticoid receptor mRNA levels in fetal guinea-pig hippocampal neurons, in vitro

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Quantification of hormone-induced atrophy of large myotubes from C2C12 and L6 cells: atrophy-inducible and atrophy-resistant C2C12 myotubes

5 July 2018

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GSK-3beta inhibitors reduce protein degradation in muscles from septic rats and in dexamethasone-treated myotubes

5 July 2018

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Insulin-like growth factor-I inhibits dexamethasone-induced proteolysis in cultured L6 myotubes through PI3K/Akt/GSK-3beta and PI3K/Akt/mTOR-dependent mechanisms

5 July 2018

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Dexamethasone upregulates the expression of the nuclear cofactor p300 and its interaction with C/EBPbeta in cultured myotubes

5 July 2018

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Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway

5 July 2018

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IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

5 July 2018

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The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

5 July 2018

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Dexamethasone regulates endothelin-1 and endothelin receptors in human non-pigmented ciliary epithelial (HNPE) cells

5 July 2018

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RU486-induced glucocorticoid receptor agonism is controlled by the receptor N terminus and by corepressor binding

5 July 2018

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Signal transduction mechanisms mediating rapid, nongenomic effects of cortisol on prolactin release

5 July 2018

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Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

5 July 2018

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Identification of ubiquitin ligases required for skeletal muscle atrophy

5 July 2018

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Dantrolene reduces serum TNFalpha and corticosterone levels and muscle calcium, calpain gene expression, and protein breakdown in septic rats

5 July 2018

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5 July 2018

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5 July 2018

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Among translational effectors, p70S6k is uniquely sensitive to inhibition by glucocorticoids

5 July 2018

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Stimulation of myofibrillar protein degradation and expression of mRNA encoding the ubiquitin-proteasome system in C(2)C(12) myotubes by dexamethasone: effect of the proteasome inhibitor MG-132.

5 July 2018

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5 July 2018

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Dexamethasone stimulates proteasome- and calcium-dependent proteolysis in cultured L6 myotubes.

5 July 2018

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Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle

5 July 2018

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Effects of dexamethasone and anabolic agents on proliferation and protein synthesis and degradation in C2C12 myogenic cells

5 July 2018

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Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids

5 July 2018

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Sepsis stimulates nonlysosomal, energy-dependent proteolysis and increases ubiquitin mRNA levels in rat skeletal muscle

5 July 2018

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Effects of dexamethasone on protein degradation and protease gene expression in rat L8 myotube cultures

5 July 2018

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Retention of differentiation potentialities during prolonged cultivation of myogenic cells

5 July 2018

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5 July 2018

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Influence of anabolic agents on protein synthesis and degradation in muscle cells grown in culture.

5 July 2018

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Hormonal and metabolic response to recombinant human tumor necrosis factor in rat: in vitro and in vivo

5 July 2018

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

5 July 2018

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Blockade of glucocorticoid receptor binding and inhibition of dexamethasone-induced muscle atrophy in the rat by RU38486, a potent glucocorticoid antagonist

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901105

Interaction between corticosterone and tumor necrosis factor stimulated protein breakdown in rat skeletal muscle, similar to sepsis

5 July 2018

1 reference

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Effect of the glucocorticoid receptor antagonist RU 38486 on muscle protein breakdown in sepsis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901105

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901105

Tumour necrosis factor (TNF) and interleukin-1 (IL-1) induce muscle proteolysis through different mechanisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901105

Tissue-specific regulation of ubiquitin (UbC) transcription by glucocorticoids: in vivo and in vitro analyses

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901105

Sepsis stimulates calpain activity in skeletal muscle by decreasing calpastatin activity but does not activate caspase-3.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901105

IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901105

Delineation of signalling pathway leading to antioxidant-dependent inhibition of dexamethasone-mediated muscle cell death.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901105

C2C12 myocytes lack an insulin-responsive vesicular compartment despite dexamethasone-induced GLUT4 expression.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901105

Rapid activation of ERK1/2 mitogen-activated protein kinase by corticosterone in PC12 cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2901105

Changes in body composition and dietary intake induced by tumor necrosis factor alpha and corticosterone--individually and in combination

29 October 2018

1 reference

12 December 2020

Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle

1 reference

12 December 2020

Cytokine modulation by PX differently affects specific acute phase proteins during sepsis in rats

1 reference

12 December 2020

Glucocorticoid-recognizing and -effector sites in rat liver plasma membrane. Kinetics of corticosterone uptake by isolated membrane vesicles. III. Specificity and stereospecificity

1 reference

12 December 2020

Influence of burn injury on protein metabolism in different types of skeletal muscle and the role of glucocorticoids

1 reference

12 December 2020

Burn-induced increase in atrogin-1 and MuRF-1 in skeletal muscle is glucocorticoid independent but downregulated by IGF-I

1 reference

12 December 2020

The pivotal role of cytokines in muscle wasting during cancer

1 reference

12 December 2020

The expression of genes in the ubiquitin-proteasome proteolytic pathway is increased in skeletal muscle from patients with cancer

1 reference

12 December 2020

Specific binding of dexamethasone to plasma membranes from skeletal muscle

1 reference

12 December 2020

Proteasome proteolytic activity in skeletal muscle is increased in patients with sepsis

1 reference

12 December 2020

Glucocorticoids induce proteasome C3 subunit expression in L6 muscle cells by opposing the suppression of its transcription by NF-kappa B

1 reference

12 December 2020

Expression and activity of C/EBPbeta and delta are upregulated by dexamethasone in skeletal muscle

1 reference

12 December 2020

Identifiers

DOI

10.1002/JCB.21833

1 reference

30 July 2017

1 reference

30 July 2017

1 reference