Accommodating haploinsufficient tumor suppressor genes in Knudson's model (Q33986221)

30 July 2017

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title

Accommodating haploinsufficient tumor suppressor genes in Knudson's model (English)

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30 July 2017

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Cook WD

1

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30 July 2017

McCaw BJ

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 July 2000

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30 July 2017

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30 July 2017

volume

19

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30 July 2017

issue

30

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30 July 2017

page(s)

3434-3438

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Deletions of chromosome 20q and the pathogenesis of myeloproliferative disorders

30 July 2017

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The murine gene p27Kip1 is haplo-insufficient for tumour suppression

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The genetics of Wilms' tumor--a case of disrupted development

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Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

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Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

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Tumor suppressor mutations in mice: the next generation

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Mechanisms of p53 loss in human sarcomas

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

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Mutations in the p53 gene occur in diverse human tumour types

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Early loss of the retinoblastoma gene is associated with impaired growth inhibitory innervation during melanotroph carcinogenesis in Rb+/- mice

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

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p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

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Two Li-Fraumeni syndrome families with novel germline p53 mutations: loss of the wild-type p53 allele in only 50% of tumours

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Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders

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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

21 January 2018

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Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

21 January 2018

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Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

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Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1-1.5 Mb and preparation of a PAC-based physical map.

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inferred from DOI database lookup

7 January 2021

based on heuristic

Delineation of multiple deleted regions in 7q in myeloid disorders

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1203653

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Dimensions Publication ID

30 July 2017

1048659608

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1 reference