Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells (Q33995584)

30 July 2017

Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells (English)

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30 July 2017

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S Mehdi Belgnaoui

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30 July 2017

Roger G Gosden

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2

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30 July 2017

O John Semmes

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30 July 2017

Abdelali Haoudi

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30 July 2017

language of work or name

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2 May 2006

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Cancer Cell International

30 July 2017

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30 July 2017

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30 July 2017

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https://scigraph.springernature.com/pub.10.1186/1475-2867-6-13

30 July 2017

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cites work

Gamma radiation increases endonuclease-dependent L1 retrotransposition in a cultured cell assay

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The human LINE-1 retrotransposon creates DNA double-strand breaks.

5 July 2018

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A potential role for RNA interference in controlling the activity of the human LINE-1 retrotransposon

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Cell-cycle checkpoints and cancer

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Retrotransposition-Competent Human LINE-1 Induces Apoptosis in Cancer Cells With Intactp53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Histone H2AX is phosphorylated at sites of retroviral DNA integration but is dispensable for postintegration repair.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

DNA damage responses to oxidative stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

DNA damage tumor suppressor genes and genomic instability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

DNA damage-induced apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

5 July 2018

1 reference

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Mobile elements: drivers of genome evolution

5 July 2018

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Human T-cell leukemia virus-I tax oncoprotein functionally targets a subnuclear complex involved in cellular DNA damage-response

5 July 2018

1 reference

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Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Evidence that the retroviral DNA integration process triggers an ATR-dependent DNA damage response

5 July 2018

1 reference

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Tracking an embryonic L1 retrotransposition event

5 July 2018

1 reference

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Kinetics of human immunodeficiency virus type 1 (HIV) DNA integration in acutely infected cells as determined using a novel assay for detection of integrated HIV DNA.

5 July 2018

1 reference

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Activation of Ty transposition by mutagens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Initial sequencing and analysis of the human genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Human L1 retrotransposition: cis preference versus trans complementation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Wortmannin potentiates integrase-mediated killing of lymphocytes and reduces the efficiency of stable transduction by retroviruses.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Determination of L1 retrotransposition kinetics in cultured cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

A role for DNA-PK in retroviral DNA integration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Sequence-specific single-strand RNA binding protein encoded by the human LINE-1 retrotransposon

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

High frequency retrotransposition in cultured mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Reverse Transcriptase Encoded by a Human Transposable Element

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

A potential role for the nucleolus in L1 retrotransposition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464142

Genomic deletions created upon LINE-1 retrotransposition

29 October 2018

1 reference

12 December 2020

Identification of critical CpG sites for repression of L1 transcription by DNA methylation

1 reference

12 December 2020

Human l1 retrotransposition is associated with genetic instability in vivo

1 reference

12 December 2020

V(D)J recombination and transposition: closer than expected

1 reference

12 December 2020

Identifiers

DOI

10.1186/1475-2867-6-13

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Dimensions Publication ID

30 July 2017

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30 July 2017

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