HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease (Q33998193)

30 July 2017

title

HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease (English)

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30 July 2017

9

Ludvig M Sollid

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30 July 2017

7

Günther Jung

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30 July 2017

6

William W Kwok

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30 July 2017

4

Oyvind Molberg

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30 July 2017

Stig Tollefsen

1

1 reference

30 July 2017

Helene Arentz-Hansen

2

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30 July 2017

Burkhard Fleckenstein

3

1 reference

30 July 2017

Melinda Ráki

5

1 reference

30 July 2017

Knut E A Lundin

8

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30 July 2017

language of work or name

English

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publication date

27 July 2006

1 reference

Journal of Clinical Investigation

30 July 2017

published in

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30 July 2017

volume

116

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30 July 2017

issue

8

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30 July 2017

page(s)

2226-2236

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MHC class II proteins and disease: a structural perspective

30 July 2017

cites work

1 reference

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The insulin A-chain epitope recognized by human T cells is posttranslationally modified

5 July 2018

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5 July 2018

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Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity

5 July 2018

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Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation

5 July 2018

1 reference

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Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease

5 July 2018

1 reference

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Intestinal T-cell responses to high-molecular-weight glutenins in celiac disease

5 July 2018

1 reference

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Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues

5 July 2018

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Genetic control of autoimmunity in Type I diabetes and associated disorders

5 July 2018

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The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides

5 July 2018

1 reference

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GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes

5 July 2018

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High selectivity of human tissue transglutaminase for immunoactive gliadin peptides: implications for celiac sprue

5 July 2018

1 reference

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Characterization of preparations of GAD65, proinsulin, and the islet tyrosine phosphatase IA-2 for use in detection of autoreactive T-cells in type 1 diabetes: report of phase II of the Second International Immunology of Diabetes Society Workshop fo

5 July 2018

1 reference

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Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes

5 July 2018

1 reference

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Structural principles of MHC class II antigen presentation

5 July 2018

1 reference

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Molecular basis of celiac disease

5 July 2018

1 reference

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In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope.

5 July 2018

1 reference

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The intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase

5 July 2018

1 reference

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Production of a panel of recombinant gliadins for the characterisation of T cell reactivity in coeliac disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Impaired binding of a DQ2 and DQ8-binding HSV VP16 peptide to a DQA1*0501/DQB1*0302 trans class II heterodimer

5 July 2018

1 reference

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Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Use of eluted peptide sequence data to identify the binding characteristics of peptides to the insulin-dependent diabetes susceptibility allele HLA-DQ8 (DQ 3.2).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Invited anniversary review: HLA associated diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Peptide binding characteristics of the coeliac disease-associated DQ(alpha1*0501, beta1*0201) molecule

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Allele-specific motifs characterize HLA-DQ interactions with a diabetes-associated peptide derived from glutamic acid decarboxylase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

HLA-DQ allelic polymorphisms constrain patterns of class II heterodimer formation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Structural analysis of a human I-A homologue using a monoclonal antibody that recognizes an MB3-like specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

HLA-DQ molecules form alpha-beta heterodimers of mixed allotype.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

MHC class-II molecules and autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease-associated HLA-DQ2 molecule.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Characterization of an HLA-DQ2-specific monoclonal antibody. Influence of amino acid substitutions in DQ beta 1*0202.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Human T4+ and T8+ cytotoxic T lymphocyte clones directed at products of different class II major histocompatibility complex loci.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1518792

Identification of a putative motif for binding of peptides to HLA-DQ2

29 October 2018

1 reference

12 December 2020

Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls

1 reference

12 December 2020

Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity

1 reference

12 December 2020

Identification of a gliadin T-cell epitope in coeliac disease: general importance of gliadin deamidation for intestinal T-cell recognition

1 reference

12 December 2020

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

1 reference

12 December 2020

1 reference

12 December 2020

HLA genotype distribution and genetic models of insulin-dependent diabetes mellitus

1 reference

12 December 2020

Transcomplementation of HLA genes in IDDM. HLA-DQ alpha- and beta-chains produce hybrid molecules in DR3/4 heterozygotes

1 reference

12 December 2020

Characterization of specific HLA-DQ alpha allospecificities by genomic, biochemical, and serologic analysis

1 reference

12 December 2020

Glutenin is involved in the gluten-driven mucosal T cell response

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI27620

1 reference

30 July 2017

1 reference

30 July 2017

1 reference