Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expression (Q34000784)

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English	Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expression	scientific article

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Sulforaphane- and phenethyl isothiocyanate-induced inhibition of aflatoxin B1-mediated genotoxicity in human hepatocytes: role of GSTM1 genotype and CYP3A4 gene expression (English)

1 reference

Europe PubMed Central

30 July 2017

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Stephen C Strom

object named as

Stephen C Strom

5

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author name string

Kerstin Gross-Steinmeyer

1

1 reference

Europe PubMed Central

30 July 2017

Patricia L Stapleton

2

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Europe PubMed Central

30 July 2017

Julia H Tracy

3

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Europe PubMed Central

30 July 2017

Theo K Bammler

4

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Europe PubMed Central

30 July 2017

David L Eaton

6

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Europe PubMed Central

30 July 2017

publication date

4 May 2010

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Europe PubMed Central

30 July 2017

Toxicological Sciences

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Europe PubMed Central

30 July 2017

116

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Europe PubMed Central

30 July 2017

2

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Europe PubMed Central

30 July 2017

422-432

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Europe PubMed Central

30 July 2017

Modulation of aflatoxin B1-mediated genotoxicity in primary cultures of human hepatocytes by diindolylmethane, curcumin, and xanthohumols

1 reference

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GST polymorphism and excretion of heterocyclic aromatic amine and isothiocyanate metabolites after Brassica consumption

1 reference

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Chemopreventive effects of natural dietary compounds on cancer development

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Molecular basis for chemoprevention by sulforaphane: a comprehensive review.

1 reference

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5 July 2018

Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.

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Inhibition of angiogenesis and endothelial cell functions are novel sulforaphane-mediated mechanisms in chemoprevention.

1 reference

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Polymorphism of glutathione S-transferase mu 1 and theta 1 genes and hepatocellular carcinoma in southern Guangxi, China

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A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

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Interindividual differences in response to chemoprotection against aflatoxin-induced hepatocarcinogenesis: implications for human biotransformation enzyme polymorphisms.

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Peanut butter intake, GSTM1 genotype and hepatocellular carcinoma: a case-control study in Sudan

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Activation and detoxication of aflatoxin B1

1 reference

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Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes.

1 reference

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The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4.

1 reference

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5 July 2018

Chronic hepatitis B carriers with null genotypes of glutathione S-transferase M1 and T1 polymorphisms who are exposed to aflatoxin are at increased risk of hepatocellular carcinoma

1 reference

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Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates

1 reference

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Mechanisms of aflatoxin carcinogenesis

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Bioactive organosulfur phytochemicals in Brassica oleracea vegetables--a review

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Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture.

1 reference

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The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor.

1 reference

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29 October 2018

A study about the association of detoxication gene GSTM1 polymorphism and the susceptibility to aflatoxin B1-related hepatocellular carcinoma

1 reference

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Influence of Matrigel-overlay on constitutive and inducible expression of nine genes encoding drug-metabolizing enzymes in primary human hepatocytes

1 reference

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Hepatocellular carcinoma and polymorphisms in carcinogen-metabolizing and DNA repair enzymes in a population with aflatoxin exposure and hepatitis B virus endemicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905401

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Phytochemical-induced changes in gene expression of carcinogen-metabolizing enzymes in cultured human primary hepatocytes

1 reference

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A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905401

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Susceptibility to aflatoxin B1-related primary hepatocellular carcinoma in mice and humans.

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Polycyclic aromatic hydrocarbon-DNA adducts in liver tissues of hepatocellular carcinoma patients and controls

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Expression of human microsomal epoxide hydrolase in Saccharomyces cerevisiae reveals a functional role in aflatoxin B1 detoxification.

1 reference

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Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans

1 reference

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Genetic polymorphisms of glutathione S-transferases M1 and T1 associated with susceptibility to aflatoxin-related hepatocarcinogenesis among chronic hepatitis B carriers: a nested case-control study in Taiwan

1 reference

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Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: mechanisms of inducible resistance to aflatoxin B1.

1 reference

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29 October 2018

Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/20442190

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Cytochrome P450 2E1 and glutathione S-transferase M1 polymorphisms and susceptibility to hepatocellular carcinoma

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Use of human hepatocytes to study P450 gene induction

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https://pubmed.ncbi.nlm.nih.gov/20442190

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Molecular and genetic epidemiology of hepatocellular carcinoma: studies in China and Senegal

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https://pubmed.ncbi.nlm.nih.gov/20442190

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Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20442190

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Determinants of the variability of aflatoxin-albumin adduct levels in Ghanaians

1 reference

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Effect of meal composition and cooking duration on the fate of sulforaphane following consumption of broccoli by healthy human subjects

1 reference

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Associations of plasma aflatoxin B1-albumin adduct level with plasma selenium level and genetic polymorphisms of glutathione S-transferase M1 and T1

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Statistical Methods for Identifying Differentially Expressed Genes in DNA Microarrays

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10.1093/TOXSCI/KFQ135

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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