Cell death beyond apoptosis (Q34002890)

30 July 2017

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title

Cell death beyond apoptosis (English)

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30 July 2017

1

Blagosklonny MV

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30 July 2017

1 August 2000

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30 July 2017

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30 July 2017

14

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30 July 2017

8

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30 July 2017

1502-1508

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2401864

30 July 2017

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cites work

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Caspases and apoptosis – biology and terminology

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Death in Embryonic Systems

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Caspase-independent programmed cell death with necrotic morphology

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Protein or RNA synthesis inhibition induces apoptosis of mature human CD4+ T cell blasts

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Constitutive expression of the machinery for programmed cell death

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptosis by death factor

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Death receptors: signaling and modulation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Caspases: enemies within

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptotic pathways: the roads to ruin

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Mechanisms mediating caspase activation in cell death

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Mitochondria and apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Involvement of caspase 3-activated DNase in internucleosomal DNA cleavage induced by diverse apoptotic stimuli

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Extranuclear apoptosis. The role of the cytoplasm in the execution phase

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptosis: cell death defined by caspase activation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Cisplatin induces apoptosis in a human ovarian carcinoma cell line without concomitant internucleosomal degradation of DNA.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Lack of internucleosomal DNA fragmentation is related to Cl(-) efflux impairment in hematopoietic cell apoptosis.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Mechanisms of induction of apoptotic DNA fragmentation.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Interdigital cell death can occur through a necrotic and caspase-independent pathway.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Camptothecin-induced apoptosis in p53-null human leukemia HL60 cells and their isolated nuclei: effects of the protease inhibitors Z-VAD-fmk and dichloroisocoumarin suggest an involvement of both caspases and serine proteases

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Caspase activation without death

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptosis without caspases: an inefficient molecular guillotine?

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptosis and drug response

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Double identity for proteins of the Bcl-2 family

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Conversion of Bcl-2 to a Bax-like death effector by caspases

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

A matter of life and cell death

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

A node between proliferation, apoptosis, and growth arrest

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Janus faces of ras: anti or pro-apoptotic?

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: suppression by mutant c-H-ras oncogene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Differential regulation of discrete apoptotic pathways by Ras.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Induced mitotic death of HeLa cells by abnormal expression of c-H-ras

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Proteasome-dependent regulation of p21WAF1/CIP1 expression

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Growth factor modulation of p53-mediated growth arrest versus apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Constitutive Raf-1 kinase activity in breast cancer cells induces both estrogen-independent growth and apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Induction of cell death by stimulation of protein kinase C in human epithelial cells expressing a mutant ras oncogene: a potential therapeutic target

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

The mitogen-activated protein kinase pathway mediates growth arrest or E1A-dependent apoptosis in SKBR3 human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Inhibition of caspase proteases by CrmA enhances the resistance of human leukemic cells to multiple chemotherapeutic agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Inhibited apoptosis and drug resistance in acute myeloid leukaemia.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptosis and resistance to daunorubicin in human leukemic cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Clinical significance of CD95, Bcl-2 and Bax expression and CD95 function in adult de novo acute myeloid leukemia in context of P-glycoprotein function, maturation stage, and cytogenetics.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Resistance to apoptosis induced by serum depletion and all-trans retinoic acid in drug-resistant leukemic cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptotic response to camptothecin and 7-hydroxystaurosporine (UCN-01) in the 8 human breast cancer cell lines of the NCI Anticancer Drug Screen: multifactorial relationships with topoisomerase I, protein kinase C, Bcl-2, p53, MDM-2 and caspase path

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Signaling defect in the activation of caspase-3 and PKCdelta in human TUR leukemia cells is associated with resistance to apoptosis.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Association of high molecular weight DNA fragmentation with apoptotic or non-apoptotic cell death induced by calcium ionophore

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Drug-induced apoptosis in chronic lymphocytic leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptosis in cancer therapy: crossing the threshold

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

UCN-01, a protein kinase C inhibitor, inhibits endothelial cell proliferation and angiogenic hypoxic response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Activation of the cell death program by inhibition of proteasome function

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

The role of the ubiquitin-proteasome pathway in apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptosis in leukocytes.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

1 reference

7 January 2021

Dysregulation of apoptosis in cancer

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

P53, cell cycle control and apoptosis: implications for cancer

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptosis in antitumor strategies: modulation of cell cycle or differentiation.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptosis in human disease: a new skin for the old ceremony?

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Apoptosis as a goal of cancer therapy

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Selective killing of transformed baby hamster kidney (BHK) cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

A Restriction Point for Control of Normal Animal Cell Proliferation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Pretreatment with DNA-damaging agents permits selective killing of checkpoint-deficient cells by microtubule-active drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Drug-resistance enables selective killing of resistant leukemia cells: exploiting of drug resistance instead of reversal.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401864

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2401864

1 reference

PubMed ID

10942250

Dimensions Publication ID

30 July 2017

0 references

1 reference

PubMed ID

10942250