Macrophage fatty-acid synthase deficiency decreases diet-induced atherosclerosis (Q34004031)

30 July 2017

Macrophage fatty-acid synthase deficiency decreases diet-induced atherosclerosis (English)

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30 July 2017

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1 reference

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Jochen G Schneider

1

1 reference

30 July 2017

Zhen Yang

2

1 reference

30 July 2017

Manu V Chakravarthy

3

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30 July 2017

Irfan J Lodhi

4

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30 July 2017

Xiaochao Wei

5

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30 July 2017

John Turk

6

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30 July 2017

Clay F Semenkovich

7

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30 July 2017

language of work or name

English

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publication date

17 May 2010

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Journal of Biological Chemistry

30 July 2017

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30 July 2017

285

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30 July 2017

23398-23409

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30 July 2017

30

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Induction of fatty acid synthesis is a key requirement for phagocytic differentiation of human monocytes

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Forecasting the effects of obesity and smoking on U.S. life expectancy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Identification of a physiologically relevant endogenous ligand for PPARalpha in liver

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

The crystal structure of a mammalian fatty acid synthase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Decreased fetal size is associated with beta-cell hyperfunction in early life and failure with age.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Atherosclerosis inflammation imaging with 18F-FDG PET: carotid, iliac, and femoral uptake reproducibility, quantification methods, and recommendations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Fatty acid synthase inhibitors: new directions for oncology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Macrophage beta3 integrin suppresses hyperlipidemia-induced inflammation by modulating TNFalpha expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

PPARalpha deficiency reduces insulin resistance and atherosclerosis in apoE-null mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Prediction of Coronary Heart Disease Using Risk Factor Categories

28 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

28 July 2018

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Regulation of fatty acid synthase (FAS).

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Dietary polyunsaturated fatty acids and composition of human aortic plaques.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Effects of starvation and different culture conditions on the phospholipid content of isolated pancreatic islets.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Lipid droplets in atherosclerotic fatty streaks of human aorta

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

De novo synthesis and elongation of fatty acids by subcellar fractions of monkey aorta.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Fatty acid biosynthesis in aorta and heart

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Sudden death: lessons from subsets in population studies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Does the predictive value of baseline coronary risk factors change over a 30-year follow-up?

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Intensive lipid lowering with atorvastatin in patients with stable coronary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Cholesterol, triglyceride, and phospholipid content of intima, media, and atherosclerotic fatty streak in human thoracic aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Dietary trans fatty acids and composition of human atheromatous plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Relation of plaque lipid composition and morphology to the stability of human aortic plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Lipide synthesis in aorta preparations from atherosclerosis-susceptible or resistant pigeons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

"New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

As macrophages indulge, atherosclerotic lesions bulge

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Respiratory uncoupling lowers blood pressure through a leptin-dependent mechanism in genetically obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Selective activation of liver X receptors by acanthoic acid-related diterpenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARalpha, PPARgamma, and LXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Differential effects of chronic, in vivo, PPAR's stimulation on the myocardial subcellular redistribution of FAT/CD36 and FABPpm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Identification of macrophage liver X receptors as inhibitors of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Effect of macrophage overexpression of murine liver X receptor-alpha (LXR-alpha) on atherosclerosis in LDL-receptor deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Macrophage ATP-binding cassette transporter A1 overexpression inhibits atherosclerotic lesion progression in low-density lipoprotein receptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.100321

Human fatty acid synthase mRNA: tissue distribution, genetic mapping, and kinetics of decay after glucose deprivation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906331

Protein synthesis inhibition in mouse peritoneal macrophages results in increased acyl coenzyme A:cholesterol acyl transferase activity and cholesteryl ester accumulation in the presence of native low density lipoprotein

29 October 2018

1 reference

12 December 2020

Decreased arachidonate metabolism in mouse peritoneal macrophages after foam cell transformation with oxidized low-density lipoproteins

1 reference

12 December 2020

LIPID BIOSYNTHESIS IN AORTIC INTIMA FROM NORMAL AND CHOLESTEROL-FED RABBITS

1 reference

12 December 2020

LIPID METABOLISM IN PIGEON AORTA DURING ATHEROGENESIS

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.100321

1 reference

30 July 2017

1 reference

30 July 2017

1 reference