Impact of tissue plasminogen activator on the neurovascular unit: from clinical data to experimental evidence (Q34006140)

30 July 2017

1 reference

title

Impact of tissue plasminogen activator on the neurovascular unit: from clinical data to experimental evidence (English)

1 reference

30 July 2017

1 reference

Maxime Gauberti

2

0 references

Denis Vivien

object named as

Denis Vivien

1

0 references

Emmanuel Touzé

object named as

Emmanuel Touzé

5

0 references

author name string

Axel Montagne

3

1 reference

30 July 2017

Gilles Defer

4

1 reference

30 July 2017

publication date

31 August 2011

1 reference

Journal of Cerebral Blood Flow & Metabolism

30 July 2017

published in

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30 July 2017

volume

31

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30 July 2017

issue

11

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30 July 2017

page(s)

2119-2134

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Tissue plasminogen activator prevents white matter damage following stroke

30 July 2017

cites work

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5 July 2018

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Good clinical outcome after ischemic stroke with successful revascularization is time-dependent

5 July 2018

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Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke: pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II Trials

5 July 2018

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5 July 2018

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5 July 2018

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Efficacy and safety of tissue plasminogen activator 3 to 4.5 hours after acute ischemic stroke: a metaanalysis.

5 July 2018

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Outcomes of intravenous tissue plasminogen activator for acute ischemic stroke in patients aged 90 years or older

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke

5 July 2018

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5 July 2018

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Differential regulation of matrix metalloproteinase-9 and tissue plasminogen activator activity by the cyclic-AMP system in lipopolysaccharide-stimulated rat primary astrocytes

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Mouse model of in situ thromboembolic stroke and reperfusion

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia

5 July 2018

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Ethanol-withdrawal seizures are controlled by tissue plasminogen activator via modulation of NR2B-containing NMDA receptors

5 July 2018

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Rapid, activity-induced increase in tissue plasminogen activator is mediated by metabotropic glutamate receptor-dependent mRNA translation

5 July 2018

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Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling

5 July 2018

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Equivocal roles of tissue-type plasminogen activator in stroke-induced injury

5 July 2018

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Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.

5 July 2018

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Ultrasound in the treatment of ischaemic stroke

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Extracellular proteolysis in brain injury and inflammation: role for plasminogen activators and matrix metalloproteinases

5 July 2018

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Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: the Multicenter rt-PA Stroke Survey

5 July 2018

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5 July 2018

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Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II)

5 July 2018

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The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

5 July 2018

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5 July 2018

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Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice

5 July 2018

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Thrombolysis with tissue plasminogen activator alters adhesion molecule expression in the ischemic rat brain

5 July 2018

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Inflammation and glial responses in ischemic brain lesions

5 July 2018

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Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

5 July 2018

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5 July 2018

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Tissue plasminogen activator for acute ischemic stroke

5 July 2018

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Pharmacokinetics and systemic effects of tissue-type plasminogen activator in normal subjects

5 July 2018

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Inhibition of plasminogen activator inhibitor-1 activity results in promotion of endogenous thrombolysis and inhibition of thrombus extension in models of experimental thrombosis

5 July 2018

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Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke

5 July 2018

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Relationship of blood pressure, antihypertensive therapy, and outcome in ischemic stroke treated with intravenous thrombolysis: retrospective analysis from Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SIT

5 July 2018

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Association of admission blood glucose and outcome in patients treated with intravenous thrombolysis: results from the Safe Implementation of Treatments in Stroke International Stroke Thrombolysis Register (SITS-ISTR).

21 January 2018

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Neutralizing the neurotoxic effects of exogenous and endogenous tPA.

21 January 2018

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NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity

21 January 2018

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Anti-NR1 N-terminal-domain vaccination unmasks the crucial action of tPA on NMDA-receptor-mediated toxicity and spatial memory.

21 January 2018

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Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial

21 January 2018

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Monoclonal antibodies preventing leukocyte activation reduce experimental neurologic injury and enhance efficacy of thrombolytic therapy

21 January 2018

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Plasma cellular-fibronectin concentration predicts hemorrhagic transformation after thrombolytic therapy in acute ischemic stroke.

21 January 2018

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Serum cellular fibronectin and matrix metalloproteinase-9 as screening biomarkers for the prediction of parenchymal hematoma after thrombolytic therapy in acute ischemic stroke: a multicenter confirmatory study.

21 January 2018

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Melatonin attenuates the postischemic increase in blood-brain barrier permeability and decreases hemorrhagic transformation of tissue-plasminogen activator therapy following ischemic stroke in mice

21 January 2018

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Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage

21 January 2018

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Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial

21 January 2018

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21 January 2018

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Speed of tPA-induced clot lysis predicts DWI lesion evolution in acute stroke.

21 January 2018

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Intra-arterial thrombolysis for acute ischemic stroke: preliminary experience with platelet glycoprotein IIb/IIIa inhibitors as adjunctive therapy

21 January 2018

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Safety of intravenous thrombolysis for acute ischemic stroke in patients receiving antiplatelet therapy at stroke onset

21 January 2018

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Intravenous alteplase for stroke in those older than 80 years old.

21 January 2018

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Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials

21 January 2018

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Hemorrhagic transformation and microvascular integrity during focal cerebral ischemia/reperfusion

21 January 2018

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Plasma VAP-1/SSAO activity predicts intracranial hemorrhages and adverse neurological outcome after tissue plasminogen activator treatment in stroke.

21 January 2018

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Acute intravenous--intra-arterial revascularization therapy for severe ischemic stroke.

21 January 2018

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Combined intravenous and intra-arterial recanalization for acute ischemic stroke: the Interventional Management of Stroke Study

21 January 2018

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Predictors for malignant middle cerebral artery infarctions: a postmortem analysis

21 January 2018

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Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity

21 January 2018

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Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C.

21 January 2018

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Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity.

21 January 2018

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Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects

21 January 2018

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Results of a multicentre, randomised controlled trial of intra-arterial urokinase in the treatment of acute posterior circulation ischaemic stroke.

21 January 2018

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Antibodies preventing the interaction of tissue-type plasminogen activator with N-methyl-D-aspartate receptors reduce stroke damages and extend the therapeutic window of thrombolysis.

21 January 2018

1 reference

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Comparison of intravenous alteplase with a combined intravenous-endovascular approach in patients with stroke and confirmed arterial occlusion (RECANALISE study): a prospective cohort study.

21 January 2018

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Enriched housing reverses age-associated impairment of cognitive functions and tPA-dependent maturation of BDNF.

21 January 2018

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FK-506 extended the therapeutic time window for thrombolysis without increasing the risk of hemorrhagic transformation in an embolic rat stroke model

21 January 2018

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Nitric oxide mediates neurodegeneration and breakdown of the blood-brain barrier in tPA-dependent excitotoxic injury in mice

21 January 2018

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How to design an opioid drug that causes reduced tolerance and dependence

21 January 2018

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Intra-arterial reteplase and intravenous abciximab in patients with acute ischemic stroke: an open-label, dose-ranging, phase I study

21 January 2018

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The impact of recanalization on ischemic stroke outcome: a meta-analysis

21 January 2018

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Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke.

21 January 2018

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Site of arterial occlusion identified by transcranial Doppler predicts the response to intravenous thrombolysis for stroke.

21 January 2018

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Symptomatic intracerebral hemorrhage and recanalization after IV rt-PA: a multicenter study.

21 January 2018

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Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

21 January 2018

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Treatment with melagatran alone or in combination with thrombolytic therapy reduced ischemic brain injury

21 January 2018

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Rosiglitazone alone or in combination with tissue plasminogen activator improves ischemic brain injury in an embolic model in rats.

21 January 2018

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Neuronal activation of NF-kappaB contributes to cell death in cerebral ischemia.

21 January 2018

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Microglial low-density lipoprotein receptor-related protein 1 mediates the effect of tissue-type plasminogen activator on matrix metalloproteinase-9 activity in the ischemic brain

21 January 2018

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Plasminogen activator inhibitor-1 is a major determinant of arterial thrombolysis resistance.

21 January 2018

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Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II.

21 January 2018

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29 October 2018

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Fibrinolytic agents: mechanisms of activity and pharmacology.

29 October 2018

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Ultrasound-Enhanced Systemic Thrombolysis for Acute Ischemic Stroke

29 October 2018

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Low Rates of Acute Recanalization With Intravenous Recombinant Tissue Plasminogen Activator in Ischemic Stroke

21 January 2018

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Platelet/polymorphonuclear leukocyte interaction in dynamic conditions: evidence of adhesion cascade and cross talk between P-selectin and the beta 2 integrin CD11b/CD18

21 January 2018

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Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis

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12 December 2020

Endovascular administration after intravenous infusion of thrombolytic agents for the treatment of patients with acute ischemic strokes

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12 December 2020

Symptomatic intracerebral hemorrhage among eligible warfarin-treated patients receiving intravenous tissue plasminogen activator for acute ischemic stroke

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12 December 2020

Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system

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12 December 2020

Thrombolytic therapy for acute stroke--not a moment to lose

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12 December 2020

Differential pattern of tissue plasminogen activator-induced proximal middle cerebral artery recanalization among stroke subtypes

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12 December 2020

Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan

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12 December 2020

The Interventional Management of Stroke (IMS) II Study

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12 December 2020

Combined intravenous and intra-arterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial

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12 December 2020

Thrombolysis with alteplase 3-4.5 h after acute ischaemic stroke (SITS-ISTR): an observational study

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12 December 2020

[European Stroke Organisation 2008 guidelines for managing acute cerebral infarction or transient ischemic attack. Part 1]

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12 December 2020

Combined intravenous and intra-arterial recombinant tissue plasminogen activator in acute ischemic stroke

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12 December 2020

A Mouse Model of Hemorrhagic Transformation by Delayed Tissue Plasminogen Activator Administration After In Situ Thromboembolic Stroke

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12 December 2020

Treating patients with 'wake-up' stroke: the experience of the AbESTT-II trial

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Identifiers

DOI

10.1038/JCBFM.2011.127

1 reference

30 July 2017

1 reference

30 July 2017

1 reference