Cerebrolysin™ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure (Q34006701)

30 July 2017

Cerebrolysin™ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure (English)

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30 July 2017

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Edward Rockenstein

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30 July 2017

11

Eliezer Masliah

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30 July 2017

2

Kiren Ubhi

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30 July 2017

Margarita Trejo

3

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30 July 2017

Michael Mante

4

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30 July 2017

Christina Patrick

5

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30 July 2017

Anthony Adame

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30 July 2017

Philipp Novak

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30 July 2017

Marion Jech

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30 July 2017

Edith Doppler

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30 July 2017

Herbert Moessler

10

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30 July 2017

21 July 2014

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30 July 2017

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30 July 2017

15

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30 July 2017

90

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https://scigraph.springernature.com/pub.10.1186/1471-2202-15-90

30 July 2017

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Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules.

5 July 2018

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TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease

5 July 2018

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Axonopathy in an α-synuclein transgenic model of Lewy body disease is associated with extensive accumulation of C-terminal-truncated α-synuclein

5 July 2018

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GSK3beta-mediated Drp1 phosphorylation induced elongated mitochondrial morphology against oxidative stress

5 July 2018

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Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation

5 July 2018

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Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer's disease-related tau phosphorylation via PAR-1.

5 July 2018

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5 July 2018

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S-nitrosylation of Cdk5: potential implications in amyloid-β-related neurotoxicity in Alzheimer disease

5 July 2018

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Cerebrolysin improves symptoms and delays progression in patients with Alzheimer's disease and vascular dementia.

5 July 2018

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The pharmacology of neurotrophic treatment with Cerebrolysin: brain protection and repair to counteract pathologies of acute and chronic neurological disorders

5 July 2018

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Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage

5 July 2018

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Tau reduction prevents Abeta-induced defects in axonal transport.

5 July 2018

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Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors

5 July 2018

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Cerebrolysin: a review of its use in dementia

5 July 2018

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Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

5 July 2018

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Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease

5 July 2018

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Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin

5 July 2018

1 reference

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TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions

5 July 2018

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Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

5 July 2018

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Synaptic remodeling during aging and in Alzheimer's disease.

5 July 2018

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Early-onset, rapidly progressive familial tauopathy with R406W mutation.

5 July 2018

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Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease

5 July 2018

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Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

5 July 2018

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Autosomal dominant dementia with widespread neurofibrillary tangles.

5 July 2018

1 reference

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Structural correlates of cognition in dementia: quantification and assessment of synapse change.

5 July 2018

1 reference

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Mechanisms of synaptic dysfunction in Alzheimer's disease.

5 July 2018

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Relationship between plaques, tangles, and dystrophic processes in Alzheimer's disease

5 July 2018

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Quantitative assessment of cortical synaptic density in Alzheimer's disease.

5 July 2018

1 reference

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Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

5 July 2018

1 reference

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Dual effects of increased glycogen synthase kinase-3β activity on adult neurogenesis

5 July 2018

1 reference

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Elevated levels of soluble total and hyperphosphorylated tau result in early behavioral deficits and distinct changes in brain pathology in a new tau transgenic mouse model

29 October 2018

1 reference

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Combination treatment in Alzheimer's disease: results of a randomized, controlled trial with cerebrolysin and donepezil.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Efficacy and safety of Cerebrolysin in moderate to moderately severe Alzheimer's disease: results of a randomized, double-blind, controlled trial investigating three dosages of Cerebrolysin

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Spotlight on cerebrolysin in dementia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Hippocampal neuronal subpopulations are differentially affected in double transgenic mice overexpressing frontotemporal dementia and parkinsonism linked to chromosome 17 tau and glycogen synthase kinase-3beta.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Effects of Cerebrolysin on neurogenesis in an APP transgenic model of Alzheimer's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

A 24-week, double-blind, placebo-controlled study of three dosages of Cerebrolysin in patients with mild to moderate Alzheimer's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Amelioration of the cerebrovascular amyloidosis in a transgenic model of Alzheimer's disease with the neurotrophic compound cerebrolysin

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

The neuroprotective effects of Cerebrolysin in a transgenic model of Alzheimer's disease are associated with improved behavioral performance.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Staging disease severity in pathologically confirmed cases of frontotemporal dementia.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Effects of Cerebrolysin on amyloid-beta deposition in a transgenic model of Alzheimer's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Phenotypic variation in hereditary frontotemporal dementia with tau mutations.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122761

Recent advances in the understanding of the role of synaptic proteins in Alzheimer's Disease and other neurodegenerative disorders

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25047000

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2202-15-90

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Dimensions Publication ID

30 July 2017

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30 July 2017

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