Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis (Q34016565)

30 July 2017

title

Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis (English)

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30 July 2017

Abdul Waheed

1

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30 July 2017

Jeffrey H Grubb

2

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30 July 2017

Xiao Yan Zhou

3

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30 July 2017

Shunji Tomatsu

4

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30 July 2017

Robert E Fleming

5

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30 July 2017

Mark E Costaldi

6

1 reference

30 July 2017

Robert S Britton

7

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30 July 2017

Bruce R Bacon

8

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30 July 2017

William S Sly

9

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30 July 2017

language of work or name

English

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publication date

26 February 2002

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

99

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30 July 2017

issue

5

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30 July 2017

page(s)

3117-3122

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Molecular aspects of iron absorption and HFE expression

30 July 2017

cites work

1 reference

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Binding to the transferrin receptor is required for endocytosis of HFE and regulation of iron homeostasis

5 July 2018

1 reference

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Intestinal iron absorption: current concepts circa 2000.

5 July 2018

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Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

HFE downregulates iron uptake from transferrin and induces iron-regulatory protein activity in stably transfected cells.

5 July 2018

1 reference

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Experimental hemochromatosis due to MHC class I HFE deficiency: immune status and iron metabolism

5 July 2018

1 reference

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The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor

5 July 2018

1 reference

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The C282Y mutation causing hereditary hemochromatosis does not produce a null allele

5 July 2018

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Transferrin receptor is negatively modulated by the hemochromatosis protein HFE: implications for cellular iron homeostasis

5 July 2018

1 reference

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The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells

5 July 2018

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Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1

5 July 2018

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Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum

5 July 2018

1 reference

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Co-trafficking of HFE, a nonclassical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation

5 July 2018

1 reference

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Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers

5 July 2018

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Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor

5 July 2018

1 reference

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HFE gene knockout produces mouse model of hereditary hemochromatosis

5 July 2018

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The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

5 July 2018

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Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis

5 July 2018

1 reference

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Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells

5 July 2018

1 reference

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The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression

5 July 2018

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Mutation analysis of the HLA-H gene in Italian hemochromatosis patients

5 July 2018

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Control of iron absorption.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

Mutation analysis in hereditary hemochromatosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

Defective iron homeostasis in beta 2-microglobulin knockout mice recapitulates hereditary hemochromatosis in man.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

Haemochromatosis and HLA-H.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

beta2 knockout mice develop parenchymal iron overload: A putative role for class I genes of the major histocompatibility complex in iron metabolism

5 July 2018

1 reference

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Carbonic anhydrase IV: role of removal of C-terminal domain in glycosylphosphatidylinositol anchoring and realization of enzyme activity

5 July 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

5 July 2018

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Expression in mammalian cells of a gene from Streptomyces alboniger conferring puromycin resistance

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

Functional expression of the human transferrin receptor cDNA in Chinese hamster ovary cells deficient in endogenous transferrin receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

Intracellular transport blockade caused by disruption of the disulfide bridge in the third external domain of major histocompatibility complex class I antigen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

Human transferrin receptor internalization is partially dependent upon an aromatic amino acid on the cytoplasmic domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

Efficient selection for high-expression transfectants with a novel eukaryotic vector

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

Hereditary hemochromatosis. Phenotypic expression of the disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

Review of the folin phenol protein quantitation method of lowry, rosebrough, farr and randall

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

Expression of the duodenal iron transporters divalent-metal transporter 1 and ferroportin 1 in iron deficiency and iron overload

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.042701499

Wild-type HFE protein normalizes transferrin iron accumulation in macrophages from subjects with hereditary hemochromatosis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122482

Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces an iron-deficient phenotype

29 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.042701499

Hereditary haemochromatosis

21 January 2018

1 reference

12 December 2020

Transferrin receptor distribution and regulation in the rat small intestine. Effect of iron stores and erythropoiesis

1 reference

12 December 2020

Regulation of the transferrin-independent iron transport system in cultured cells

1 reference

12 December 2020

Regulation of intestinal iron absorption and mucosal iron kinetics in hereditary hemochromatosis

1 reference

12 December 2020

Regulation of transferrin, transferrin receptor, and ferritin genes in human duodenum

1 reference

12 December 2020

The major histocompatibility complex-encoded class I-like HFE abrogates endocytosis of transferrin receptor by inducing receptor phosphorylation

1 reference

12 December 2020

The endocytotic rate constant. A cellular parameter for quantitating receptor-mediated endocytosis

1 reference

12 December 2020

Localization of the sites of iodination of human .beta.2-microglobulin; quaternary structure implications for histocompatibility antigens

1 reference

12 December 2020

Haemochromatosis and HLA-H

1 reference

12 December 2020

Mutations in the MHC class I-like candidate gene for hemochromatosis in French patients

1 reference

12 December 2020

The transferrin receptor binding site on HFE, the class I MHC-related protein mutated in hereditary hemochromatosis

1 reference

12 December 2020

Duodenal metal-transporter (DMT-1, NRAMP-2) expression in patients with hereditary haemochromatosis

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.042701499

1 reference

30 July 2017

0 references

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30 July 2017

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