Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity (Q34017801)

30 July 2017

Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity (English)

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30 July 2017

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16

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30 July 2017

1

Ludmila Pawlikowska

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30 July 2017

11

Bruce M Psaty

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30 July 2017

13

Nir Barzilai

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30 July 2017

14

Steven R Cummings

1 reference

30 July 2017

5

Catherine Chu

1 reference

30 July 2017

10

Alexander P Reiner

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30 July 2017

17

Elad Ziv

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30 July 2017

Donglei Hu

2

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30 July 2017

Scott Huntsman

3

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30 July 2017

Andrew Sung

4

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30 July 2017

Justin Chen

6

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30 July 2017

Alexander H Joyner

7

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30 July 2017

Nicholas J Schork

8

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30 July 2017

Wen-Chi Hsueh

9

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30 July 2017

Gil Atzmon

12

1 reference

30 July 2017

Warren S Browner

15

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30 July 2017

Study of Osteoporotic Fractures

18

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30 July 2017

31 May 2009

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30 July 2017

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30 July 2017

8

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30 July 2017

460-472

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30 July 2017

4

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FOXO3A genotype is strongly associated with human longevity

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Functionally significant insulin-like growth factor I receptor mutations in centenarians

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Genome-wide association study identifies novel breast cancer susceptibility loci

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Lipoprotein genotype and conserved pathway for exceptional longevity in humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

A haplotype map of the human genome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Efficiency and power in genetic association studies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Haploview: analysis and visualization of LD and haplotype maps

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Unique lipoprotein phenotype and genotype associated with exceptional longevity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

In vivo mutagenesis of the insulin receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

The endocrine regulation of aging by insulin-like signals

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Homogeneous primer extension assay with fluorescence polarization detection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

A C. elegans mutant that lives twice as long as wild type

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Genes that regulate both development and longevity in Caenorhabditis elegans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Appendicular bone density and age predict hip fracture in women. The Study of Osteoporotic Fractures Research Group

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

The Cardiovascular Health Study: design and rationale

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Genes encoding longevity: from model organisms to humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

A second generation human haplotype map of over 3.1 million SNPs

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Genome-wide association studies provide new insights into type 2 diabetes aetiology

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

RNA maps reveal new RNA classes and a possible function for pervasive transcription

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Reduced insulin/IGF-1 signalling and human longevity.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3652804

Recruitment of adults 65 years and older as participants in the cardiovascular health study

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19489743

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Surveillance and ascertainment of cardiovascular events. The Cardiovascular Health Study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19489743

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1474-9726.2009.00493.X

1 reference

30 July 2017

1 reference

30 July 2017

1 reference