Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism. (Q34020622)

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English	Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism.	scientific article

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31 January 2020

Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism (English)

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31 January 2020

Parkinson's disease

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31 January 2020

Christopher A Ross

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Christopher A Ross

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31 January 2020

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Frank Gillardon

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31 January 2020

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Mali Jiang

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31 January 2020

Yair Porat-Shliom

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31 January 2020

Zhong Pei

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31 January 2020

Yong Cheng

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31 January 2020

Lan Xiang

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31 January 2020

Katherine Sommers

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31 January 2020

Qing Li

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31 January 2020

Bastian Hengerer

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31 January 2020

Cynthia Berlinicke

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31 January 2020

Wanli W Smith

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31 January 2020

Michelle A Poirier

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31 January 2020

Wenzhen Duan

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31 January 2020

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19 April 2010

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31 January 2020

Journal of Neurochemistry

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31 January 2020

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31 January 2020

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31 January 2020

419-429

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31 January 2020

Cell death pathways in Parkinson's disease: role of mitochondria

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28 July 2018

Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro

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28 July 2018

Alpha-synuclein aggregation and Ser-129 phosphorylation-dependent cell death in oligodendroglial cells.

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28 July 2018

Alpha-synuclein assembly as a therapeutic target of Parkinson's disease and related disorders

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28 July 2018

Central role of alpha-synuclein oligomers in neurodegeneration in Parkinson disease

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28 July 2018

Alpha-synuclein misfolding and neurodegenerative diseases

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28 July 2018

Structural characteristics of alpha-synuclein oligomers stabilized by the flavonoid baicalein

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28 July 2018

Parkinson's disease: clinical features and diagnosis

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28 July 2018

Dopamine differentially induces aggregation of A53T mutant and wild type alpha-synuclein: insights into the protein chemistry of Parkinson's disease

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28 July 2018

The aggregation and fibrillation of alpha-synuclein

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28 July 2018

Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system

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28 July 2018

The alpha-synuclein mutation E46K promotes aggregation in cultured cells

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28 July 2018

Baicalein attenuates 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells

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28 July 2018

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28 July 2018

The E46K mutation in alpha-synuclein increases amyloid fibril formation.

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28 July 2018

Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein

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28 July 2018

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28 July 2018

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

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28 July 2018

Caught in the act: alpha-synuclein is the culprit in Parkinson's disease

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28 July 2018

alpha-Synuclein locus triplication causes Parkinson's disease

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A protein-chameleon: conformational plasticity of alpha-synuclein, a disordered protein involved in neurodegenerative disorders

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Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

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alpha-synuclein promotes mitochondrial deficit and oxidative stress

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Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease

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28 July 2018

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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28 July 2018

The effects of the flavonoid baicalein and osmolytes on the Mg 2+ accelerated aggregation/fibrillation of carboxymethylated bovine 1SS-alpha-lactalbumin

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Cell-produced alpha-synuclein oligomers are targeted to, and impair, the 26S proteasome

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The impact of the E46K mutation on the properties of alpha-synuclein in its monomeric and oligomeric states

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21 January 2018

Baicalein prevents 6-hydroxydopamine-induced dopaminergic dysfunction and lipid peroxidation in mice

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Molecular mechanisms underlying the flavonoid-induced inhibition of alpha-synuclein fibrillation

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Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity

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The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils

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29 October 2018

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12 December 2020

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31 January 2020

release_bm35x4n6ovezpnimv24czxzzky

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31 January 2020

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