Novel peptide binds EWS-FLI1 and reduces the oncogenic potential in Ewing tumors (Q34021681)

30 July 2017

Novel peptide binds EWS-FLI1 and reduces the oncogenic potential in Ewing tumors (English)

1 reference

30 July 2017

Hayriye V Erkizan

1

1 reference

30 July 2017

Lauren J Scher

2

1 reference

30 July 2017

S Ellen Gamble

3

1 reference

30 July 2017

Julie S Barber-Rotenberg

4

1 reference

30 July 2017

Kamal P Sajwan

5

1 reference

30 July 2017

Aykut Üren

6

1 reference

30 July 2017

Jeffrey A Toretsky

7

1 reference

30 July 2017

1 October 2011

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30 July 2017

12

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based on heuristic

inferred from page(s)

published in

Cell Cycle

1 reference

30 July 2017

10

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30 July 2017

19

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30 July 2017

3397-3408

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Dynamic protein–DNA recognition: beyond what can be seen

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Cell cycle suspension: a novel process lurking in G₂ arrest

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Targeting tumor angiogenesis with TSP-1-based compounds: rational design of antiangiogenic mimetics of endogenous inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Phage display: concept, innovations, applications and future

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Intrinsically disordered proteins are potential drug targets

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Oncogenic partnerships: EWS-FLI1 protein interactions initiate key pathways of Ewing's sarcoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Mifamurtide in osteosarcoma--a practical review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

The intracellular delivery of a recombinant peptide derived from the acidic domain of PIAS3 inhibits STAT3 transactivation and induces tumor cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

The future of aptamers in medicine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Downstream EWS/FLI1 - upstream Ewing's sarcoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

A molecular function map of Ewing's sarcoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

EWS/FLI1 suppresses retinoblastoma protein function and senescence in Ewing's sarcoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family members

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

The EWS/FLI1 oncogenic transcription factor deregulates GLI1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Cell-penetrating peptides as vectors for peptide, protein and oligonucleotide delivery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Ewing's sarcoma oncoprotein EWS-FLI1: the perfect target without a therapeutic agent

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Cooperative DNA binding with AP-1 proteins is required for transformation by EWS-Ets fusion proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Rational design of shepherdin, a novel anticancer agent.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Recombinant EWS-FLI1 oncoprotein activates transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Identification of p21WAF1/CIP1 as a direct target of EWS-Fli1 oncogenic fusion protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

An integrated vector system for cellular studies of phage display-derived peptides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Interaction of the EWS NH2 terminus with BARD1 links the Ewing's sarcoma gene to a common tumor suppressor pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Downregulation and forced expression of EWS-Fli1 fusion gene results in changes in the expression of G(1)regulatory genes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

The splicing factor U1C represses EWS/FLI-mediated transactivation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

The insulin-like growth factor-I receptor is required for EWS/FLI-1 transformation of fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Examining the specificity of Src homology 3 domain--ligand interactions with alkaline phosphatase fusion proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233630

Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone

5 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.19.17734

Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.19.17734

Epigenetic maintenance of stemness and malignancy in peripheral neuroectodermal tumors by EZH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.19.17734

Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.19.17734

Stapled peptides in the p53 pathway: computer simulations reveal novel interactions of the staples with the target protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.19.17734

The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCC.10.19.17734

21 January 2018

Identifiers

DOI

10.4161/CC.10.19.17734

1 reference

release_jtg5534uyfb43pt36drsoeeysa

30 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jtg5534uyfb43pt36drsoeeysa

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

3233630

1 reference

30 July 2017

1 reference