Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic lateral sclerosis (LiCALS) [Eudract number: 2008-006891-31]. (Q34026859)

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English	Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic lateral sclerosis (LiCALS) [Eudract number: 2008-006891-31].	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic lateral sclerosis (LiCALS) [Eudract number: 2008-006891-31]. (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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amyotrophic lateral sclerosis

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placebo-controlled trial

1 reference

based on heuristic

inferred from title

Carolyn A. Young

object named as

Carolyn A Young

3

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Ammar Al-Chalabi

object named as

Ammar Al-Chalabi

1

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object named as

Pamela J Shaw

2

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Karen E Morrison

object named as

Karen E Morrison

4

0 references

9

object named as

P Nigel Leigh

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Caroline Murphy

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Marie Thornhill

6

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Joanna Kelly

7

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

I Nicholas Steen

8

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

UKMND-LiCALS

10

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

publication date

21 September 2011

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Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

11

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Europe PubMed Central

PubMed publication ID

30 July 2017

111

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Diagnosis and management of motor neurone disease

1 reference

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Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition

1 reference

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5 July 2018

Lithium delays progression of amyotrophic lateral sclerosis

1 reference

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Recombinant human insulin-like growth factor I (rhIGF-I) for amyotrophic lateral sclerosis/motor neuron disease

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Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content

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Inositol and IP3 levels regulate autophagy: biology and therapeutic speculations.

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Neuroprotective agents for clinical trials in ALS: a systematic assessment

1 reference

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5 July 2018

Lithium induces autophagy by inhibiting inositol monophosphatase

1 reference

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1 reference

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5 July 2018

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

1 reference

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5 July 2018

Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors

1 reference

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Efficacy and safety of xaliproden in amyotrophic lateral sclerosis: results of two phase III trials

1 reference

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A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons

1 reference

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The Hospital Anxiety And Depression Scale

1 reference

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5 July 2018

Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation.

1 reference

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5 July 2018

The validity of the Hospital Anxiety and Depression Scale. An updated literature review

1 reference

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5 July 2018

Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

1 reference

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5 July 2018

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

1 reference

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5 July 2018

Clinical relevance of drug interactions with lithium

1 reference

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5 July 2018

Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic lateral sclerosis

1 reference

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21 January 2018

GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila

1 reference

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21 January 2018

Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2377-11-111

21 January 2018

Glycogen synthase kinase-3beta/beta-catenin promotes angiogenic and anti-apoptotic signaling through the induction of VEGF, Bcl-2 and survivin expression in rat ischemic preconditioned myocardium

1 reference

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21 January 2018

Enhancement of neuroprotection and heat shock protein induction by combined prostaglandin A1 and lithium in rodent models of focal ischemia.

1 reference

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Lithium stimulates progenitor proliferation in cultured brain neurons.

1 reference

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A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.

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Outcome measures for early phase clinical trials.

1 reference

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Pentoxifylline in ALS: a double-blind, randomized, multicenter, placebo-controlled trial

1 reference

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Excellent inter‐rater, intra‐rater, and telephone‐administered reliability of the ALSFRS‐R in a multicenter clinical trial

1 reference

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21 January 2018

A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/21936930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II

1 reference

https://pubmed.ncbi.nlm.nih.gov/21936930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lithium--early development, toxicity, and renal function

1 reference

https://pubmed.ncbi.nlm.nih.gov/21936930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1471-2377-11-111

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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