Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides (Q34033626)

30 July 2017

Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides (English)

1 reference

30 July 2017

Agustinus R Uria

5

0 references

Neil J Oldham

object named as

Neil J Oldham

6

0 references

author name string

Michael F Freeman

1

1 reference

30 July 2017

Cristian Gurgui

2

1 reference

30 July 2017

Maximilian J Helf

3

1 reference

30 July 2017

Brandon I Morinaka

4

1 reference

30 July 2017

Hans-Georg Sahl

7

1 reference

30 July 2017

Shigeki Matsunaga

8

1 reference

30 July 2017

Jörn Piel

9

1 reference

30 July 2017

language of work or name

English

0 references

publication date

13 September 2012

1 reference

30 July 2017

1 reference

30 July 2017

338

1 reference

30 July 2017

6105

1 reference

30 July 2017

387-390

1 reference

Polytheonamides A and B, highly cytotoxic, linear polypeptides with unprecedented structural features, from the marine sponge, Theonella swinhoei

30 July 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Solution structure of polytheonamide B, a highly cytotoxic nonribosomal polypeptide from marine sponge

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Total synthesis of the large non-ribosomal peptide polytheonamide B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Nonribosomal peptide synthetases: structures and dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Follow the leader: the use of leader peptides to guide natural product biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Thiostrepton biosynthesis: prototype for a new family of bacteriocins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Rapid isolation of rare clones from highly complex DNA libraries by PCR analysis of liquid gel pools.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Mechanistic investigations of the dehydration reaction of lacticin 481 synthetase using site-directed mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Biosynthesis of the antimicrobial peptide epilancin 15X and its N-terminal lactate

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Radical-mediated enzymatic methylation: a tale of two SAMS

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Biological systems discovery in silico: radical S-adenosylmethionine protein families and their target peptides for posttranslational modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Genome mining for radical SAM protein determinants reveals multiple sactibiotic-like gene clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

CpcM posttranslationally methylates asparagine-71/72 of phycobiliprotein beta subunits in Synechococcus sp. strain PCC 7002 and Synechocystis sp. strain PCC 6803.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

A cytotoxic peptide from a marine sponge exhibits ion channel activity through vectorial-insertion into the membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Shotgun cloning and heterologous expression of the patellamide gene cluster as a strategy to achieving sustained metabolite production

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Bacterial protection of beetle-fungus mutualism

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Polyketide-chain branching by an enzymatic Michael addition

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Yaku'amides A and B, cytotoxic linear peptides rich in dehydroamino acids from the marine sponge Ceratopsion sp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Metagenomic approaches to identify and isolate bioactive natural products from microbiota of marine sponges

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

The lipopeptide antibiotic Friulimicin B inhibits cell wall biosynthesis through complex formation with bactoprenol phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1226121

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1226121

1 reference

30 July 2017

1 reference