Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha (Q34047866)

30 July 2017

Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha (English)

1 reference

30 July 2017

0 references

1 reference

Sreenivasulu Chintala

1

1 reference

30 July 2017

Károly Tóth

2

1 reference

30 July 2017

Shousong Cao

3

1 reference

30 July 2017

Farukh A Durrani

4

1 reference

30 July 2017

Mary M Vaughan

5

1 reference

30 July 2017

Randy L Jensen

6

1 reference

30 July 2017

Youcef M Rustum

7

1 reference

30 July 2017

12 January 2010

1 reference

Cancer Chemotherapy and Pharmacology

30 July 2017

1 reference

30 July 2017

66

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30 July 2017

5

1 reference

30 July 2017

899-911

1 reference

https://scigraph.springernature.com/pub.10.1007/s00280-009-1238-8

30 July 2017

0 references

cites work

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Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis

5 July 2018

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5 July 2018

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5 July 2018

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Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth

5 July 2018

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5 July 2018

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Tumor vascular maturation and improved drug delivery induced by methylselenocysteine leads to therapeutic synergy with anticancer drugs

5 July 2018

1 reference

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Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia

5 July 2018

1 reference

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The cellular adaptations to hypoxia as novel therapeutic targets in childhood cancer

5 July 2018

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A Phase I and pharmacokinetic study of selenomethionine in combination with a fixed dose of irinotecan in solid tumors

5 July 2018

1 reference

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Hypoxia-inducible factor-1 alpha contributes to hypoxia-induced chemoresistance in gastric cancer

5 July 2018

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Evaluation of HIF-1 inhibitors as anticancer agents

5 July 2018

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HIF-dependent antitumorigenic effect of antioxidants in vivo

5 July 2018

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Hypoxia in cancer: significance and impact on clinical outcome

5 July 2018

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Silencing of hypoxia inducible factor-1alpha by RNA interference attenuates human glioma cell growth in vivo.

5 July 2018

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Hypoxia signalling controls metabolic demand

5 July 2018

1 reference

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Role of hypoxia-inducible factor-1alpha as a cancer therapy target

5 July 2018

1 reference

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The mechanism of methylselenocysteine and docetaxel synergistic activity in prostate cancer cells

5 July 2018

1 reference

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Hypoxia-inducible factor-1 in human breast and prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Reversing hypoxic cell chemoresistance in vitro using genetic and small molecule approaches targeting hypoxia inducible factor-1.

5 July 2018

1 reference

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NO restores HIF-1alpha hydroxylation during hypoxia: role of reactive oxygen species.

5 July 2018

1 reference

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Small interfering RNA expression vector targeting hypoxia-inducible factor 1 alpha inhibits tumor growth in hepatobiliary and pancreatic cancers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Treatment with siRNA and antisense oligonucleotides targeted to HIF-1alpha induced apoptosis in human tongue squamous cell carcinomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Role of hypoxia-inducible factor 1alpha in gastric cancer cell growth, angiogenesis, and vessel maturation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Targeting HIF-1 for cancer therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics

5 July 2018

1 reference

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Dietary selenium repletion may reduce cancer incidence in people at high risk who live in areas with low soil selenium.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Hypoxia and drug resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: correlation with tumor oxygenation.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00280-009-1238-8

Lack of microvessels in well-differentiated regions of human head and neck squamous cell carcinoma A253 associated with functional magnetic resonance imaging detectable hypoxia, limited drug delivery, and resistance to irinotecan therapy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Methioninase cancer gene therapy with selenomethionine as suicide prodrug substrate

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Increased hypoxia correlates with increased expression of the angiogenesis marker vascular endothelial growth factor in human prostate cancer.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2916970

Organic and inorganic selenium compounds inhibit mouse mammary cell growth in vitro by different cellular pathways

10 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20066420

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Potentiation of irinotecan sensitivity by Se-methylselenocysteine in an in vivo tumor model is associated with downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and hypoxia-inducible factor 1alpha expression, resulting in reduced

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20066420

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selenium, genetic variation, and prostate cancer risk: epidemiology reflects back on selenium and vitamin E cancer prevention trial

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20066420

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00280-009-1238-8

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference