mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism (Q34053492)

30 July 2017

mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism (English)

1 reference

30 July 2017

0 references

Michael J Gandal

2

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Steven J. Siegel

object named as

Steven J Siegel

series ordinal

3

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author name string

Mili V Mehta

series ordinal

1

1 reference

PubMed ID

22016815

30 July 2017

language of work or name

English

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publication date

7 October 2011

1 reference

30 July 2017

1 reference

30 July 2017

6

1 reference

30 July 2017

10

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30 July 2017

e26077

1 reference

Creative Commons Attribution 4.0 International

30 July 2017

start time

7 October 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Validating γ oscillations and delayed auditory responses as translational biomarkers of autism

5 July 2018

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Common circuit defect of excitatory-inhibitory balance in mouse models of autism

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5 July 2018

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Group 5 metabotropic glutamate receptors: role in modulating cortical activity and relevance to cognition

5 July 2018

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Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior

5 July 2018

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Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP.

5 July 2018

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5 July 2018

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5 July 2018

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The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine

5 July 2018

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Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: citalopram ineffective in children with autism

5 July 2018

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Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

5 July 2018

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The intense world syndrome--an alternative hypothesis for autism

5 July 2018

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Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

5 July 2018

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Development of a mouse test for repetitive, restricted behaviors: relevance to autism

5 July 2018

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Mouse behavioral assays relevant to the symptoms of autism

5 July 2018

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Elevated NMDA receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acid

5 July 2018

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Risperidone for autism spectrum disorder

5 July 2018

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Animal models of restricted repetitive behavior in autism

5 July 2018

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Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder

5 July 2018

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Characteristics of fetal anticonvulsant syndrome associated autistic disorder.

5 July 2018

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Contrasting grooming phenotypes in three mouse strains markedly different in anxiety and activity (129S1, BALB/c and NMRI).

5 July 2018

1 reference

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Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome

5 July 2018

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Designing mouse behavioral tasks relevant to autistic-like behaviors

5 July 2018

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Obsessing/worrying about the overlap between obsessive-compulsive disorder and generalized anxiety disorder in youth

5 July 2018

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The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189241

Model of autism: increased ratio of excitation/inhibition in key neural systems

5 July 2018

1 reference

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In vivo receptor occupancy of mGlu5 receptor antagonists using the novel radioligand [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189241

Hoxb8 is required for normal grooming behavior in mice

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189241

Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189241

Major tranquillizers can be distinguished from minor tranquillizers on the basis of effects on marble burying and swim-induced grooming in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189241

Epidemiology of autism spectrum disorders in adults in the community in England

5 July 2018

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Restricted and repetitive behaviors in young children with autism spectrum disorders.

21 January 2018

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Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026077

Pharmacologic treatment for the core deficits and associated symptoms of autism in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026077

Autism spectrum disorders following in utero exposure to antiepileptic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026077

Behavioral alterations in rats prenatally exposed to valproic acid: animal model of autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026077

Abnormal fear conditioning and amygdala processing in an animal model of autism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026077

Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026077

Tactile sensitivity of normal and autistic children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026077

Anxiolytic-like activity of the mGluR5 antagonist MPEP: a comparison with diazepam and buspirone

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026077

Risperidone approved for the treatment of serious behavioral problems in children with autism

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189241

Risperidone for the core symptom domains of autism

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189241

Anxiolytic-like effects of the prototypical metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine in rodents.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189241

10.1371/JOURNAL.PONE.0026077

28 October 2018

Identifiers

DOI

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference

PubMed ID

22016815