Zinc finger endonuclease targeting PSIP1 inhibits HIV-1 integration (Q34058383)

30 July 2017

title

Zinc finger endonuclease targeting PSIP1 inhibits HIV-1 integration (English)

1 reference

30 July 2017

author

Bonaventura Clotet Sala

4

Bonaventura Clotet

1 reference

30 July 2017

Eduardo Pauls

2

0 references

Roger Badia

Roger Badia

1

0 references

Ester Ballana

Ester Ballana

6

0 references

José A. Esté

José A Esté

5

0 references

Eva Riveira-Muñoz

1 reference

ORCID Public Data File 2021

author name string

Eva Riveira-Munoz

3

1 reference

30 July 2017

language of work or name

English

0 references

publication date

12 May 2014

1 reference

Antimicrobial Agents and Chemotherapy

30 July 2017

published in

1 reference

30 July 2017

volume

58

1 reference

30 July 2017

issue

8

1 reference

30 July 2017

page(s)

4318-4327

1 reference

Gene editing using a zinc-finger nuclease mimicking the CCR5Δ32 mutation induces resistance to CCR5-using HIV-1.

30 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions

5 July 2018

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ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

5 July 2018

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Polymorphic LEDGF/p75 variants support efficient HIV-1 infection ex vivo

5 July 2018

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Engineered DNA modifying enzymes: components of a future strategy to cure HIV/AIDS

5 July 2018

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Characterization of LEDGF/p75 genetic variants and association with HIV-1 disease progression

5 July 2018

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The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy

5 July 2018

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HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells

5 July 2018

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HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor

5 July 2018

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5 July 2018

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Genome editing with CompoZr custom zinc finger nucleases (ZFNs).

5 July 2018

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5 July 2018

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LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs

5 July 2018

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5 July 2018

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Lens epithelium-derived growth factor/p75 qualifies as a target for HIV gene therapy in the NSG mouse model.

5 July 2018

1 reference

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Zinc finger nucleases: looking toward translation.

5 July 2018

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Hematopoietic-stem-cell-based gene therapy for HIV disease

5 July 2018

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Generation of CD34+ cells from CCR5-disrupted human embryonic and induced pluripotent stem cells

5 July 2018

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Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

5 July 2018

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An unbiased genome-wide analysis of zinc-finger nuclease specificity

5 July 2018

1 reference

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Association of polymorphisms in the LEDGF/p75 gene (PSIP1) with susceptibility to HIV-1 infection and disease progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromatin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

A TALE nuclease architecture for efficient genome editing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation

5 July 2018

1 reference

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Genome editing with engineered zinc finger nucleases

5 July 2018

1 reference

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Exploiting drug repositioning for discovery of a novel HIV combination therapy

5 July 2018

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Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

5 July 2018

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Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication

5 July 2018

1 reference

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LEDGF hybrids efficiently retarget lentiviral integration into heterochromatin

5 July 2018

1 reference

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ZNRD1 (zinc ribbon domain-containing 1) is a host cellular factor that influences HIV-1 replication and disease progression

5 July 2018

1 reference

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Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

5 July 2018

1 reference

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5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

The lentiviral integrase binding protein LEDGF/p75 and HIV-1 replication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

An essential role for LEDGF/p75 in HIV integration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

Characterization of rare lens epithelium-derived growth factor/p75 genetic variants identified in HIV-1 long-term nonprogressors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Δ32/Δ32.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

Rare LEDGF/p75 genetic variants in white long-term nonprogressor HIV+ individuals.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

β5 integrin is the major contributor to the αVintegrin-mediated blockade of HIV-1 replication

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

Cell adhesion through alphaV-containing integrins is required for efficient HIV-1 infection in macrophages

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136077

On target? Tracing zinc-finger-nuclease specificity

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24820090

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Restriction of HIV-1 Replication in Primary Macrophages by IL-12 and IL-18 through the Upregulation of SAMHD1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24820090

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.02690-14

1 reference

release_yej6wkpp6bhktplnye5g6e4ije

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yej6wkpp6bhktplnye5g6e4ije

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4136077

1 reference

30 July 2017

1 reference