GABA coordinates with insulin in regulating secretory function in pancreatic INS-1 β-cells (Q34059609)

30 July 2017

GABA coordinates with insulin in regulating secretory function in pancreatic INS-1 β-cells (English)

1 reference

30 July 2017

1 reference

Paul Bansal

1

1 reference

30 July 2017

Shuanglian Wang

2

1 reference

30 July 2017

Shenghao Liu

3

1 reference

30 July 2017

Yun-Yan Xiang

4

1 reference

30 July 2017

Wei-Yang Lu

5

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30 July 2017

Qinghua Wang

6

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30 July 2017

language of work or name

English

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publication date

21 October 2011

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30 July 2017

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30 July 2017

6

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30 July 2017

10

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30 July 2017

e26225

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Creative Commons Attribution 4.0 International

30 July 2017

start time

21 October 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes

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The role of insulin signaling in the development of β-cell dysfunction and diabetes

5 July 2018

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Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells

5 July 2018

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Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

5 July 2018

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A novel, rapid, inhibitory effect of insulin on alpha1beta2gamma2s gamma-aminobutyric acid type A receptors

5 July 2018

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Insulin as a physiological modulator of glucagon secretion

5 July 2018

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Insulin signaling in the pancreatic beta-cell

5 July 2018

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Non-steroidal anti-inflammatory drugs increase insulin release from beta cells by inhibiting ATP-sensitive potassium channels

5 July 2018

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Glucose-dependent regulation of gamma-aminobutyric acid (GABA A) receptor expression in mouse pancreatic islet alpha-cells.

5 July 2018

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ERK/MAPK pathway regulates GABAA receptors.

5 July 2018

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Critical nodes in signalling pathways: insights into insulin action

5 July 2018

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Gamma-aminobutyric acid up- and downregulates insulin secretion from beta cells in concert with changes in glucose concentration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Expression of K+-Cl- cotransporters in the alpha-cells of rat endocrine pancreas

5 July 2018

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Phosphatidylinositol 3-kinase inhibitors reveal a unique mechanism of enhancing insulin secretion in 832/13 rat insulinoma cells.

5 July 2018

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Insulin feedback actions: complex effects involving isoforms of islet nitric oxide synthase

5 July 2018

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Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses.

5 July 2018

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Gramicidin-perforated patch recording revealed the oscillatory nature of secretory Cl- movements in salivary acinar cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Zinc-mediated inhibition of GABA(A) receptors: discrete binding sites underlie subtype specificity

5 July 2018

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Is there more to GABA than synaptic inhibition?

5 July 2018

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Insulin receptor activation inhibits insulin secretion from human islets of Langerhans

5 July 2018

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Direct protein-protein coupling enables cross-talk between dopamine D5 and gamma-aminobutyric acid A receptors

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Insulin-stimulated insulin secretion in single pancreatic beta cells.

5 July 2018

1 reference

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Insulin receptor signaling in the beta-cell influences insulin gene expression and insulin content: evidence for autocrine beta-cell regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Zinc, insulin and diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Expression of functional GABAA receptors in neuroendocrine gastropancreatic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Structural stability in the 4-zinc human insulin hexamer

5 July 2018

1 reference

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Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels

5 July 2018

1 reference

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Electrophysiology of GABAA and GABAB receptor subtypes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

High Concentration of GABA and High Glutamate Decarboxylase Activity in Rat Pancreatic Islets and Human Insulinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Gamma-Aminobutyric Acid in Peripheral Tissue, with Emphasis on the Endocrine Pancreas: Presence in Two Species and Reduction by Streptozotocin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Immunohistochemical Studies of the GABA System in the Pancreas

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026225

Correlation between GABA release from rat islet beta-cells and their metabolic state

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026225

Excitatory actions of GABA in developing rat hypothalamic neurones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026225

Developmental localization of potassium chloride co-transporter 2 (KCC2), GABA and vesicular GABA transporter (VGAT) in the postnatal mouse somatosensory cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026225

Phosphatidylinositol 3-kinase suppresses glucose-stimulated insulin secretion by affecting post-cytosolic [Ca(2+)] elevation signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026225

Insulin activates ATP-sensitive K(+) channels in pancreatic beta-cells through a phosphatidylinositol 3-kinase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026225

Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026225

Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in βIRKO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026225

Presence of functional hyperpolarisation-activated cyclic nucleotide-gated channels in clonal alpha cell lines and rat islet alpha cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026225

Feedback inhibition of insulin secretion by insulin: relation to the hyperinsulinemia of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026225

Increased beta-cell apoptosis and impaired insulin signaling pathway contributes to the onset of diabetes in OLETF rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026225

Developmental up-regulation of KCC2 in the absence of GABAergic and glutamatergic transmission

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Control of synaptic strength, a novel function of Akt.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

GABA in the endocrine pancreas: cellular localization and function in normal and diabetic rats

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Modulation of the developing rat sympathetic GABAA receptor by Zn++, benzodiazepines, barbiturates and ethanol.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3198728

Nutrient regulation of gamma-aminobutyric acid release from islet beta cells

28 October 2018

1 reference

12 December 2020

Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes

1 reference

12 December 2020

Regulation of pancreatic islet cell survival and replication by gamma-aminobutyric acid

1 reference

12 December 2020

Expression of functional GABAA receptors in isolated human insulinoma cells

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0026225

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DOI

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30 July 2017

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30 July 2017

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