A mouse model to evaluate the impact of species, sex, and lipid load on lymphatic drug transport (Q34060125)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23430484%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

A mouse model to evaluate the impact of species, sex, and lipid load on lymphatic drug transport (English)

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24 February 2020

1

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24 February 2020

William N. Charman

5

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24 February 2020

Christopher J.H. Porter

6

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24 February 2020

author name string

Suzanne M Caliph

2

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24 February 2020

Gary Nguyen

3

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24 February 2020

Patrick Tso

4

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24 February 2020

publication date

21 February 2013

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24 February 2020

published in

Pharmaceutical Research

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24 February 2020

volume

30

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24 February 2020

issue

12

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24 February 2020

page(s)

3254-3270

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Strategies to address low drug solubility in discovery and development.

24 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Targeting the lymphatics using dendritic polymers (dendrimers).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Using the lymphatics to study nutrient absorption and the secretion of gastrointestinal hormones

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Comparable population pharmacokinetics and pharmacodynamic breakpoints of cefpirome in cystic fibrosis patients and healthy volunteers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Development of a new pre- and post-processing tool (SADAPT-TRAN) for nonlinear mixed-effects modeling in S-ADAPT.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Phase 2, randomized, double-blind, dose-ranging study evaluating the safety, tolerability, population pharmacokinetics, and efficacy of oral torezolid phosphate in patients with complicated skin and skin structure infections.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

A survey of population analysis methods and software for complex pharmacokinetic and pharmacodynamic models with examples

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

CD36 is important for chylomicron formation and secretion and may mediate cholesterol uptake in the proximal intestine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Contribution of lymphatic transport to the systemic exposure of orally administered moxidectin in conscious lymph duct-cannulated dogs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Animal models for the study of intestinal lymphatic drug transport

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Lymphatic transport of halofantrine in the triple-cannulated anesthetized rat model: effect of lipid vehicle dispersion.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Partitioning of polar fatty acids into lymph and portal vein after intestinal absorption in the rat.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Portal transport of absorbed lipids in rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

Uptake of lipophilic drugs by plasma derived isolated chylomicrons: linear correlation with intestinal lymphatic bioavailability

5 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

An examination of the interplay between enterocyte-based metabolism and lymphatic drug transport in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

A conscious dog model for assessing the absorption, enterocyte-based metabolism, and intestinal lymphatic transport of halofantrine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Intestinal lymphatic transport enhances the post-prandial oral bioavailability of a novel cannabinoid receptor agonist via avoidance of first-pass metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Contribution of lymphatically transported testosterone undecanoate to the systemic exposure of testosterone after oral administration of two andriol formulations in conscious lymph duct-cannulated dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Lymphatic transport of Methylnortestosterone undecanoate (MU) and the bioavailability of methylnortestosterone are highly sensitive to the mass of coadministered lipid after oral administration of MU.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Intravenous dosing conditions may affect systemic clearance for highly lipophilic drugs: implications for lymphatic transport and absolute bioavailability studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Oral bioavailability assessment and intestinal lymphatic transport of Org 45697 and Org 46035, two highly lipophilic novel immunomodulator analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Comparison of total oral bioavailability and the lymphatic transport of halofantrine from three different unsaturated triglycerides in lymph-cannulated conscious rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Bile increases intestinal lymphatic drug transport in the fasted rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

The effect of general anesthesia on the intestinal lymphatic transport of lipophilic drugs: comparison between anesthetized and freely moving conscious rat models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

The lymph lipid precursor pool is a key determinant of intestinal lymphatic drug transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Intestinal lymphatic transport of halofantrine occurs after oral administration of a unit-dose lipid-based formulation to fasted dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

A kinetic evaluation of the absorption, efflux, and metabolism of verapamil in the autoperfused rat jejunum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Acute hypertriglyceridemia promotes intestinal lymphatic lipid and drug transport: a positive feedback mechanism in lipid and drug absorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Why does the gut choose apolipoprotein B48 but not B100 for chylomicron formation?

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136478

A simplified liquid chromatography assay for the quantitation of halofantrine and desbutylhalofantrine in plasma and identification of a degradation product of desbutylhalofantrine formed under alkaline conditions

28 October 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Lymphatic Transport of Halofantrine in the Conscious Rat When Administered as Either the Free Base or the Hydrochloride Salt: Effect of Lipid Class and Lipid Vehicle Dispersion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-1000-0

Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival

21 January 2018

1 reference

12 December 2020

Effect of short-, medium-, and long-chain fatty acid-based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymph-cannulated and non-cannulated rats

1 reference

12 December 2020

Differential transport of cholesterol and oleic acid in lymph lipoproteins: sex differences in puromycin sensitivity

1 reference

12 December 2020

Mesenteric lymph apolipoproteins in control and ethinyl estradiol-treated rats: a model for studying apolipoproteins of intestinal origin

1 reference

12 December 2020

Intestinal triglycerides are derived from both endogenous and exogenous sources

1 reference

12 December 2020

Steady-state kinetic analysis of triacylglycerol delivery into mesenteric lymph

1 reference

12 December 2020

Testing for the equality of area under the curves when using destructive measurement techniques

1 reference

12 December 2020

Pentadecanoic acid-5-C14; its absorption and lymphatic transport

1 reference

12 December 2020

Intestinal lymph as pathway for transport of absorbed fatty acids of different chain lengths

1 reference

12 December 2020

The portal transport of absorbed fatty acids

1 reference

12 December 2020

The Role of the Intestinal Lymphatics in the Absorption of Two Highly Lipophilic Cholesterol Ester Transfer Protein Inhibitors (CP524,515 and CP532,623)

1 reference

12 December 2020

The mechanism of lymphatic access of two cholesteryl ester transfer protein inhibitors (CP524,515 and CP532,623) and evaluation of their impact on lymph lipoprotein profiles

1 reference

12 December 2020

10.1007/S11095-013-1000-0

Identifiers

DOI

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24 February 2020

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24 February 2020

PubMed publication ID

23430484

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