Molecular genetics and target site specificity of retroviral integration (Q34063962)

30 July 2017

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title

Molecular genetics and target site specificity of retroviral integration (English)

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30 July 2017

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Holmes-Son ML

1

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30 July 2017

Appa RS

series ordinal

2

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30 July 2017

Chow SA

series ordinal

3

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30 July 2017

publication date

1 January 2001

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30 July 2017

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30 July 2017

volume

43

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30 July 2017

page(s)

33-69

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Structural determinants of metal-induced conformational changes in HIV-1 integrase

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

A metal-induced conformational change and activation of HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Changes in the helical repeat of poly(dG-m5 dC) · poly(dG-m5dC) and poly(dG-dC) · poly(dG-dC) associated with the B—Z transition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Target-sequence preferences of HIV-1 integration complexes in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

A nucleoprotein complex mediates the integration of retroviral DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Evidence for opposite groove-directed curvature of GGGCCC and AAAAA sequence elements

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

High-resolution structure of the catalytic domain of avian sarcoma virus integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Retroviral DNA integration directed by HIV integration protein in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Ty3 integrates within the region of RNA polymerase III transcription initiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Multiple integrase functions are required to form the native structure of the human immunodeficiency virus type I intasome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

In VitroAssays for Activities of Retroviral Integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

A role for DNA-PK in retroviral DNA integration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Integration of the yeast retrotransposon Ty1 is targeted to regions upstream of genes transcribed by RNA polymerase III

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The DNA-binding domain of HIV-1 integrase has an SH3-like fold

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

An essential interaction between distinct domains of HIV-1 integrase mediates assembly of the active multimer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

HIV integrase structure and function.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Complementation of integrase function in HIV-1 virions.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Retroviral DNA integration: Structure of an integration intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The core domain of HIV-1 integrase recognizes key features of its DNA substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Stereospecificity of reactions catalyzed by HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Genetics of retroviral integration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Host site selection for concerted integration by human immunodeficiency virus type-1 virions in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Mapping features of HIV-1 integrase near selected sites on viral and target DNA molecules in an active enzyme-DNA complex by photo-cross-linking.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

A cluster of strong topoisomerase II cleavage sites is located near an integrated human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Hotspots for unselected Ty1 transposition events on yeast chromosome III are near tRNA genes and LTR sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Retroviral integrase domains: DNA binding and the recognition of LTR sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5

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https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

A preferred target DNA structure for retroviral integrase in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Targeting of retroviral integrase by fusion to a heterologous DNA binding domain: in vitro activities and incorporation of a fusion protein into viral particles

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https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The retroviral enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Adjacent pol II and pol III promoters: transcription of the yeast retrotransposon Ty3 and a target tRNA gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Requirement of RNA polymerase III transcription factors for in vitro position-specific integration of a retroviruslike element

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Mechanistic analysis of RNA polymerase III regulation by the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Yeast SNF2/SWI2, SNF5, and SNF6 proteins function coordinately with the gene-specific transcriptional activators GAL4 and Bicoid

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The SNF5 protein of Saccharomyces cerevisiae is a glutamine- and proline-rich transcriptional activator that affects expression of a broad spectrum of genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Zinc stimulates Mg2+-dependent 3'-processing activity of human immunodeficiency virus type 1 integrase in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Solution structure of the DNA binding domain of HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Structural basis for DNA bending by the architectural transcription factor LEF-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Nucleotide sequences at host–proviral junctions for mouse mammary tumour virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

DNA bending creates favored sites for retroviral integration: an explanation for preferred insertion sites in nucleosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Characterization of the minimal DNA-binding domain of the HIV integrase protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Zinc finger phage: affinity selection of fingers with new DNA-binding specificities

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https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Retroviral integrases and their cousins

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https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Structure of the nucleosome core particle at 7 Å resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Sequence periodicities in chicken nucleosome core DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Transcriptionally active genome regions are preferred targets for retrovirus integration.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Disruption of the terminal base pairs of retroviral DNA during integration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Central core domain of retroviral integrase is responsible for target site selection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Characterization of feline immunodeficiency virus integrase and analysis of functional domains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Highly preferred targets for retrovirus integration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Sequence of retrovirus provirus resembles that of bacterial transposable elements

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The human immunodeficiency virus integrase protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

A large nucleoprotein assembly at the ends of the viral DNA mediates retroviral DNA integration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Retroviral Reverse Transcription and Integration: Progress and Problems

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Distribution of targets for avian retrovirus DNA integration in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Crystal structures of catalytic core domains of retroviral integrases and role of divalent cations in enzymatic activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Localization of DNA binding activity of HIV-1 integrase to the C-terminal half of the protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Characterization of a DNA binding domain in the C-terminus of HIV-1 integrase by deletion mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Functional RT and IN incorporated into HIV-1 particles independently of the Gag/Pol precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The Saccharomyces retrotransposon Ty5 integrates preferentially into regions of silent chromatin at the telomeres and mating loci

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Structure-based mutagenesis of the human immunodeficiency virus type 1 DNA attachment site: effects on integration and cDNA synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Mutations in the human immunodeficiency virus type 1 integrase D,D(35)E motif do not eliminate provirus formation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Functional domains of Moloney murine leukemia virus integrase defined by mutation and complementation analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Mapping domains of retroviral integrase responsible for viral DNA specificity and target site selection by analysis of chimeras between human immunodeficiency virus type 1 and visna virus integrases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Mapping viral DNA specificity to the central region of integrase by using functional human immunodeficiency virus type 1/visna virus chimeric proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Incorporation of functional human immunodeficiency virus type 1 integrase into virions independent of the Gag-Pol precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Oligomerization within virions and subcellular localization of human immunodeficiency virus type 1 integrase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Structure-based mutational analysis of the C-terminal DNA-binding domain of human immunodeficiency virus type 1 integrase: critical residues for protein oligomerization and DNA binding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Sequences in the human immunodeficiency virus type 1 U3 region required for in vivo and in vitro integration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

3'-end processing and kinetics of 5'-end joining during retroviral integration in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

DNA substrate requirements for different activities of the human immunodeficiency virus type 1 integrase protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Dissecting the role of the N-terminal domain of human immunodeficiency virus integrase by trans-complementation analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

Functional interactions of the HHCC domain of moloney murine leukemia virus integrase revealed by nonoverlapping complementation and zinc-dependent dimerization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2801%2943003-3

7 January 2021

10.1016/S0065-2660(01)43003-3

Identifiers

DOI

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30 July 2017

1 reference