Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps (Q34064080)

30 July 2017

title

Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps (English)

1 reference

Argonaute RISC catalytic subunit 2

30 July 2017

main subject

1 reference

CCR4-NOT transcription complex, subunit 7

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Chyi-Ying A Chen

1

1 reference

30 July 2017

Dinghai Zheng

series ordinal

2

1 reference

30 July 2017

Zhenfang Xia

series ordinal

3

1 reference

30 July 2017

Ann-Bin Shyu

series ordinal

4

1 reference

30 July 2017

publication date

18 October 2009

1 reference

Nature Structural & Molecular Biology

30 July 2017

published in

1 reference

30 July 2017

volume

16

1 reference

30 July 2017

issue

11

1 reference

30 July 2017

page(s)

1160-1166

1 reference

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation

30 July 2017

cites work

1 reference

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Functional dissection of the human TNRC6 (GW182-related) family of proteins

5 July 2018

1 reference

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Mammalian GW182 contains multiple Argonaute-binding sites and functions in microRNA-mediated translational repression

5 July 2018

1 reference

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The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921184

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing

5 July 2018

1 reference

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Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression.

5 July 2018

1 reference

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5 July 2018

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5 July 2018

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Deadenylation is a widespread effect of miRNA regulation

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells

5 July 2018

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Computational analysis of miRNA-mediated repression of translation: implications for models of translation initiation inhibition

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Getting to the root of miRNA-mediated gene silencing

5 July 2018

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Epstein-Barr virus-encoded microRNA miR-BART2 down-regulates the viral DNA polymerase BALF5.

5 July 2018

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Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2.

5 July 2018

1 reference

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GW182 family proteins are crucial for microRNA-mediated gene silencing

5 July 2018

1 reference

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Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system

5 July 2018

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An mRNA m7G cap binding-like motif within human Ago2 represses translation

5 July 2018

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5 July 2018

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MicroRNAs silence gene expression by repressing protein expression and/or by promoting mRNA decay.

5 July 2018

1 reference

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How do microRNAs regulate gene expression?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921184

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921184

Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921184

MicroRNAs direct rapid deadenylation of mRNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921184

Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

5 July 2018

1 reference

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5 July 2018

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A role for the P-body component GW182 in microRNA function

5 July 2018

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Disruption of GW bodies impairs mammalian RNA interference

5 July 2018

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5 July 2018

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5 July 2018

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Inhibition of translational initiation by Let-7 MicroRNA in human cells

5 July 2018

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5 July 2018

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

5 July 2018

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5 July 2018

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Argonaute2 is the catalytic engine of mammalian RNAi

5 July 2018

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MicroRNA-directed cleavage of HOXB8 mRNA

5 July 2018

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Rapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathway

5 July 2018

1 reference

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5 July 2018

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A microRNA in a multiple-turnover RNAi enzyme complex

5 July 2018

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A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex

5 July 2018

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RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

5 July 2018

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A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy

5 July 2018

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AU-rich elements: characterization and importance in mRNA degradation

5 July 2018

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5 July 2018

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5 July 2018

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Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay

5 July 2018

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GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

5 July 2018

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https://api.crossref.org/works/10.1038%2FNSMB.1709

Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis

21 January 2018

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21 January 2018

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.1709

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference