Variant-type PML-RAR(alpha) fusion transcript in acute promyelocytic leukemia: use of a cryptic coding sequence from intron 2 of the RAR(alpha) gene and identification of a new clinical subtype resistant to retinoic acid therapy (Q34064907)

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English	Variant-type PML-RAR(alpha) fusion transcript in acute promyelocytic leukemia: use of a cryptic coding sequence from intron 2 of the RAR(alpha) gene and identification of a new clinical subtype resistant to retinoic acid therapy	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Variant-type PML-RAR(alpha) fusion transcript in acute promyelocytic leukemia: use of a cryptic coding sequence from intron 2 of the RAR(alpha) gene and identification of a new clinical subtype resistant to retinoic acid therapy (English)

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30 July 2017

acute promyelocytic leukemia

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based on heuristic

inferred from title

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15

object named as

Samuel Waxman

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30 July 2017

author name string

Bai-Wei Gu

1

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30 July 2017

Hui Xiong

2

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30 July 2017

Yan Zhou

3

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30 July 2017

Bing Chen

4

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30 July 2017

Li Wang

5

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30 July 2017

Shuo Dong

6

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30 July 2017

Zhi-Yuan Yu

7

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30 July 2017

Ling-Feng Lu

8

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30 July 2017

Ming Zhong

9

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30 July 2017

Hai-Feng Yin

10

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30 July 2017

Gen-Feng Zhu

11

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30 July 2017

Wei Huang

12

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30 July 2017

Shuang-Xi Ren

13

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30 July 2017

Robert E Gallagher

14

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30 July 2017

Guo-Qiang Chen

16

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30 July 2017

Zhu-Gang Wang

17

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30 July 2017

Zhu Chen

18

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30 July 2017

Gang Fu

19

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30 July 2017

Sai-Juan Chen

20

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30 July 2017

language of work or name

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publication date

1 May 2002

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30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

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30 July 2017

99

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30 July 2017

11

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30 July 2017

7640-7645

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30 July 2017

Differentiation and apoptosis induction therapy in acute promyelocytic leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Genomic sequence, structural organization, molecular evolution, and aberrant rearrangement of promyelocytic leukemia zinc finger gene

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5 July 2018

Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Structural organization of the human TOP2A and TOP2B genes.

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5 July 2018

Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

All-trans-retinoic acid in acute promyelocytic leukemia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Repression of retinoic acid-induced transactivation by embryonal LTR binding protein.

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5 July 2018

Breakpoint clusters of the PML gene in acute promyelocytic leukemia: primary structure of the reciprocal products of the PML-RARA gene in a patient with t(15;17).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Characterization of acute promyelocytic leukemia cases with PML-RAR alpha break/fusion sites in PML exon 6: identification of a subgroup with decreased in vitro responsiveness to all-trans retinoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Characterization of a functional promoter for the human retinoic acid receptor-alpha (hRAR-alpha)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Embryonal long terminal repeat-binding protein is a murine homolog of FTZ-F1, a member of the steroid receptor superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

A PML/retinoic acid receptor alpha fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Multiplicity generates diversity in the retinoic acid signalling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

5 July 2018

Genomic structure of the human retinoic acid receptor-alpha1 gene

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.112194799

21 January 2018

Analysis of the joining sequences of the t(15;17) translocation in human acute promyelocytic leukemia: sequence non-specific recombination between the PML and RARA genes within identical short stretches

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.112194799

21 January 2018

Identification of illegitimate recombination hot spot of the retinoic acid receptor alpha gene involved in 15;17 chromosomal translocation of acute promyelocytic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124308

28 October 2018

Localization of the chromosome 15 breakpoints and expression of multiple PML-RAR alpha transcripts in acute promyelocytic leukemia: a study of 28 Chinese patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/12032336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12032336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute promyelocytic leukemia: clinical relevance of two major PML-RAR alpha isoforms and detection of minimal residual disease by retrotranscriptase/polymerase chain reaction to predict relapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/12032336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular analysis and clinical outcome of adult APL patients with the type V PML-RARalpha isoform: results from intergroup protocol 0129

1 reference

https://pubmed.ncbi.nlm.nih.gov/12032336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12032336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular rearrangements of the MYL gene in acute promyelocytic leukemia (APL, M3) define a breakpoint cluster region as well as some molecular variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/12032336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Occurrence of distinct PML-RAR-alpha fusion gene isoforms in patients with acute promyelocytic leukemia detected by reverse transcriptase/polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12032336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular analysis of the PML/RAR alpha chimeric gene in pediatric acute promyelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12032336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunophenotype of adult and childhood acute promyelocytic leukaemia: correlation with morphology, type of PML gene breakpoint and clinical outcome. A cooperative Italian study on 196 cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12032336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rearrangements in the second intron of the RARA gene are present in a large majority of patients with acute promyelocytic leukemia and are used as molecular marker for retinoic acid-induced leukemic cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12032336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.112194799

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

2002PNAS...99.7640G

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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