Microbial toxins and the glycosylation of rho family GTPases (Q34066508)

30 July 2017

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title

Microbial toxins and the glycosylation of rho family GTPases (English)

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30 July 2017

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Busch C

1

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30 July 2017

Aktories K

series ordinal

2

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30 July 2017

publication date

1 October 2000

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Current Opinion in Structural Biology

30 July 2017

published in

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30 July 2017

volume

10

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30 July 2017

issue

5

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30 July 2017

page(s)

528-535

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Neurotoxins affecting neuroexocytosis

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Rho proteins: targets for bacterial toxins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Large clostridial cytotoxins--a family of glycosyltransferases modifying small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Clostridium difficile infection

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Glucosylation of Rho proteins by Clostridium difficile toxin B.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Inactivation of Ras by Clostridium sordellii lethal toxin-catalyzed glucosylation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Ras, Rap, and Rac small GTP-binding proteins are targets for Clostridium sordellii lethal toxin glucosylation.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Clostridium novyi alpha-toxin-catalyzed incorporation of GlcNAc into Rho subfamily proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

A novel cytotoxin from Clostridium difficile serogroup F is a functional hybrid between two other large clostridial cytotoxins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Genetic rearrangements in the pathogenicity locus of Clostridium difficile strain 8864--implications for transcription, expression and enzymatic activity of toxins A and B.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Clostridium difficile toxins A and B are cation-dependent UDP-glucose hydrolases with differing catalytic activities

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Rho GTPases and signaling networks

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https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Rho GTPases control polarity, protrusion, and adhesion during cell movement

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Untying the Gordian knot of cytokinesis. Role of small G proteins and their regulators

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Inhibition of Fc epsilon-RI-mediated activation of rat basophilic leukemia cells by Clostridium difficile toxin B (monoglucosyltransferase)

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Rho GTPases and their effector proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Crystal structure of RhoA-GDP and its functional implications

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Impact of amino acids 22-27 of Rho-subfamily GTPases on glucosylation by the large clostridial cytotoxins TcsL-1522, TcdB-1470 and TcdB-8864.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Functional consequences of monoglucosylation of Ha-Ras at effector domain amino acid threonine 35.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Glucosylation and ADP ribosylation of rho proteins: effects on nucleotide binding, GTPase activity, and effector coupling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Monoglucosylation of RhoA at threonine 37 blocks cytosol-membrane cycling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Clostridium difficile toxin B induces reorganization of actin, vinculin, and talin in cultured cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Inhibition of receptor signaling to phospholipase D by Clostridium difficile toxin B. Role of Rho proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Inhibition of calcium release-activated calcium current by Rac/Cdc42-inactivating clostridial cytotoxins in RBL cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

A role for the small molecular weight GTPases, Rho and Cdc42, in muscarinic receptor signaling to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Rho family proteins modulate rapid apoptosis induced by cytotoxic T lymphocytes and Fas.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

The role of local actin instability in axon formation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Localization of the glucosyltransferase activity of Clostridium difficile toxin B to the N-terminal part of the holotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Evidence for a modular structure of the homologous repetitive C-terminal carbohydrate-binding sites of Clostridium difficile toxins and Streptococcus mutans glucosyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Rabbit sucrase-isomaltase contains a functional intestinal receptor for Clostridium difficile toxin A.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Molecular mimicry in the recognition of glycosphingolipids by Gal alpha 3 Gal beta 4 GlcNAc beta-binding Clostridium difficile toxin A, human natural anti alpha-galactosyl IgG and the monoclonal antibody Gal-13: characterization of a binding-active

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Cellular internalisation of Clostridium difficile toxin A.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

pH-induced conformational changes in Clostridium difficile toxin B

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

A common motif of eukaryotic glycosyltransferases is essential for the enzyme activity of large clostridial cytotoxins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Structure/function studies of glycosyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Characterization of the glycosyltransferase enzyme from the Escherichia coli K5 capsule gene cluster and identification and characterization of the glucuronyl active site.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Characterization of chitin synthase 2 of Saccharomyces cerevisiae. Implication of two highly conserved domains as possible catalytic sites

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Structure-function analysis of the UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase. Essential residues lie in a predicted active site cleft resembling a lactose repressor fold

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Activity of the yeast MNN1 alpha-1,3-mannosyltransferase requires a motif conserved in many other families of glycosyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Conserved structural regions involved in the catalytic mechanism of Escherichia coli K-12 WaaO (RfaI).

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Involvement of a conserved tryptophan residue in the UDP-glucose binding of large clostridial cytotoxin glycosyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Structure of the nucleotide-diphospho-sugar transferase, SpsA from Bacillus subtilis, in native and nucleotide-complexed forms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Crystal structures of the bovine beta 4galactosyltransferase catalytic domain and its complex with uridine diphosphogalactose

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Hydrophobic cluster analysis: an efficient new way to compare and analyse amino acid sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Expression cloning of a new member of the ABO blood group glycosyltransferases, iGb3 synthase, that directs the synthesis of isoglobo-glycosphingolipids

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Expression cloning of a human alpha1, 4-N-acetylglucosaminyltransferase that forms GlcNAcalpha1-->4Galbeta-->R, a glycan specifically expressed in the gastric gland mucous cell-type mucin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Structural consequences of mono-glucosylation of Ha-Ras by Clostridium sordellii lethal toxin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

Capsular polysaccharide synthesis in Streptococcus pneumoniae serotype 14: molecular analysis of the complete cps locus and identification of genes encoding glycosyltransferases required for the biosynthesis of the tetrasaccharide subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900126-3

7 January 2021

10.1016/S0959-440X(00)00126-3

Identifiers

DOI

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30 July 2017

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