Negative selection of thymocytes expressing the D10 TCR (Q34067924)

30 July 2017

Negative selection of thymocytes expressing the D10 TCR (English)

1 reference

30 July 2017

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2

Charles A Janeway

1 reference

30 July 2017

1

Derek B Sant'Angelo

1 reference

PubMed ID

12011450

30 July 2017

language of work or name

English

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publication date

1 May 2002

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

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30 July 2017

99

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30 July 2017

6931-6936

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30 July 2017

10

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Evaluating peptide repertoires within the context of thymocyte development

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

T-cell development: a role for self-peptides in positive selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Cellular and biochemical requirements for thymocyte negative selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Antigen presentation and T cell development in H2-M-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

T-cell-receptor affinity and thymocyte positive selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

The specificity and orientation of a TCR to its peptide-MHC class II ligands

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

The ligand for positive selection of T lymphocytes in the thymus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Thymic selection: two pathways to life and two to death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Positive selection of thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Deletion of high-avidity T cells by thymic epithelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

The Fab fragment of a directly activating monoclonal antibody that precipitates a disulfide-linked heterodimer from a helper T cell clone blocks activation by either allogeneic Ia or antigen and self-Ia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Positive and negative selection of an antigen receptor on T cells in transgenic mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Phenotypic differences between alpha beta versus beta T-cell receptor transgenic mice undergoing negative selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

The thymus selects the useful, neglects the useless and destroys the harmful

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Asymmetry in the recognition of antigen: self class II MHC and non-self class II MHC molecules by the same T-cell receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Negative selection of precursor thymocytes before their differentiation into CD4+CD8+ cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Developmental regulation of thymocyte susceptibility to deletion by "self"-peptide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

In vivo and in vitro clonal deletion of double-positive thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Peptide-induced positive selection of TCR transgenic thymocytes in a coreceptor-independent manner.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

The repertoire of T cells shaped by a single MHC/peptide ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Rearrangement and diversity of T cell receptor beta chain genes in thymocytes: a critical role for the beta chain in development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Influence of antigen density on degree of clonal deletion in T cell receptor transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Negative selection of T cells occurs throughout thymic development

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124506

Negative selection by endogenous antigen and superantigen occurs at multiple thymic sites

28 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

On the role of high- and low-abundance class II MHC–peptide complexes in the thymic positive selection of CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

21 January 2018

Getting into the groove

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Role of self-peptides in positively selecting the T-cell repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Unexpected expression of a unique mixed-isotype class II MHC molecule by transfected L-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous α- and β-genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

The imprint of intrathymic self-peptides on the mature T cell receptor repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Requirement for diverse, low-abundance peptides in positive selection of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Positive and negative thymocyte selection induced by different concentrations of a single peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Comparison of thymocyte development in normal and invariant chain-deficient mice provides evidence that maturation-related changes in TCR and co-receptor levels play a critical role in cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

A role for accessibility to self-peptide-self-MHC complexes in intrathymic negative selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Receptor editing in developing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

The use of the polymerase chain reaction to map CD4+ T cell epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

An MHC interaction site maps to the amino-terminal half of the T cell receptor α chain variable domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Inhibition of the responses of a cloned CD4+ T cell line to different class II major histocompatibility complex ligands by anti-CD4 and by anti-receptor Fab fragments are directly related

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Premature TCR alpha beta expression and signaling in early thymocytes impair thymocyte expansion and partially block their development

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Identification of a naturally occurring ligand for thymic positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

The thymus and central tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

T lymphocyte tolerance: from thymic deletion to peripheral control mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Ligand thresholds at different stages of T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102182499

Cutting edge: negative selection of immature thymocytes by a few peptide-MHC complexes: differential sensitivity of immature and mature T cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12011450

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12011450

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.102182499

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference

PubMed ID

12011450