Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity (Q34070890)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20101208%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity (English)

1 reference

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17 January 2020

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1 reference

1

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17 January 2020

Domenico Iacopetta

2

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17 January 2020

author name string

K R Covington

3

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17 January 2020

Y Cui

4

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17 January 2020

A Tsimelzon

5

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17 January 2020

A Beyer

6

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17 January 2020

S Andò

7

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17 January 2020

S A W Fuqua

8

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17 January 2020

language of work or name

English

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publication date

25 January 2010

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17 January 2020

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17 January 2020

volume

29

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17 January 2020

issue

16

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17 January 2020

page(s)

2404-2414

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https://scigraph.springernature.com/pub.10.1038/onc.2009.520

17 January 2020

exact match

0 references

cites work

Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway

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Growth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor alpha and its phosphorylation at serine 305.

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Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor

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P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation

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The estrogen receptor-alpha A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study

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Acquired resistance to oestrogen deprivation: role for growth factor signalling kinases/oestrogen receptor cross-talk revealed in new MCF-7X model.

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Phosphorylation of the oestrogen receptor alpha at serine 305 and prediction of tamoxifen resistance in breast cancer

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21 January 2018

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Phosphorylation of estrogen receptor alpha, serine residue 305 enhances activity

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20101208

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A hypersensitive estrogen receptor-alpha mutation in premalignant breast lesions

1 reference

PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2009.520

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20101208%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20101208%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference