Akt phosphorylation of La regulates specific mRNA translation in glial progenitors (Q39932300)

15 September 2017

title

Akt phosphorylation of La regulates specific mRNA translation in glial progenitors (English)

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15 September 2017

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F Brenet

1

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15 September 2017

N D Socci

series ordinal

2

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15 September 2017

N Sonenberg

series ordinal

3

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15 September 2017

E C Holland

series ordinal

4

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15 September 2017

language of work or name

English

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publication date

6 October 2008

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15 September 2017

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15 September 2017

volume

28

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15 September 2017

issue

1

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15 September 2017

page(s)

128-139

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Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein

15 September 2017

cites work

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BRF1 protein turnover and mRNA decay activity are regulated by protein kinase B at the same phosphorylation sites

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Mammalian peptidylglycine alpha-amidating monooxygenase mRNA expression can be modulated by the La autoantigen

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Detailed analysis of the phosphorylation of the human La (SS-B) autoantigen. (De)phosphorylation does not affect its subcellular distribution

21 January 2018

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La protein is associated with terminal oligopyrimidine mRNAs in actively translating polysomes

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La protein has a positive effect on the translation of TOP mRNAs in vivo

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Phase I and pharmacological study of daily oral administration of perifosine (D-21266) in patients with advanced solid tumours

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PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

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Structure of the La motif: a winged helix domain mediates RNA binding via a conserved aromatic patch

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Akt-mediated YB-1 phosphorylation activates translation of silent mRNA species

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5' processing of tRNA precursors can Be modulated by the human La antigen phosphoprotein

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The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling

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Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

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4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

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Translational control and metastatic progression: enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs

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Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro

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The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2.

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Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

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Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes

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Differential phosphorylation and subcellular localization of La RNPs associated with precursor tRNAs and translation-related mRNAs.

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La autoantigen enhances translation of BiP mRNA

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Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

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Autophosphorylation of Akt at threonine 72 and serine 246. A potential mechanism of regulation of Akt kinase activity

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Role of the RNA-binding protein HuR in colon carcinogenesis

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Hitting the target: emerging technologies in the search for kinase substrates

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Synthesis of the translational apparatus is regulated at the translational level

21 January 2018

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Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo

21 January 2018

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Akt phosphorylates and regulates Pdcd4 tumor suppressor protein

21 January 2018

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Postgenomic global analysis of translational control induced by oncogenic signaling

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Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes

21 January 2018

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The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis

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Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays

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Mammary tumor induction in transgenic mice expressing an RNA-binding protein

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BCR/ABL activates mdm2 mRNA translation via the La antigen

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Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

21 January 2018

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The yeast La protein is required for the 3' endonucleolytic cleavage that matures tRNA precursors

21 January 2018

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Shuttling of the autoantigen La between nucleus and cell surface after uv irradiation of human keratinocytes

21 January 2018

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A cellular protein that binds to the 5'-noncoding region of poliovirus RNA: implications for internal translation initiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.376

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.376

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15 September 2017

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