Apoptosis modulators in the therapy of neurodegenerative diseases (Q34074800)

30 July 2017

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title

Apoptosis modulators in the therapy of neurodegenerative diseases (English)

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30 July 2017

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Deigner HP

1

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30 July 2017

Haberkorn U

series ordinal

2

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30 July 2017

Kinscherf R

series ordinal

3

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30 July 2017

language of work or name

English

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publication date

1 April 2000

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Expert Opinion on Investigational Drugs

30 July 2017

published in

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30 July 2017

volume

9

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30 July 2017

issue

4

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30 July 2017

page(s)

747-764

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Etiology and pathogenesis of Parkinson's disease

30 July 2017

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

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The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)

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Analysis of apoptosis by laser scanning cytometry

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Apoptosis: a novel therapeutic tool?

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An introduction to the free radical hypothesis in Parkinson's disease

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Oxidative stress and apoptosis in neurodegeneration

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Apoptosis in neurodegenerative diseases: the role of mitochondria

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Cell death and apoptosis regulating proteins in Parkinson's disease--a cautionary note

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Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease

21 January 2018

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Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors

21 January 2018

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Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease

21 January 2018

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Antioxidant properties of 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone (idebenone).

21 January 2018

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Inhibitory effect of the neuroprotective agent idebenone on arachidonic acid metabolism in astrocytes

21 January 2018

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Melatonin protects hippocampal neurons in vivo against kainic acid-induced damage in mice

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Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

21 January 2018

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The nonfibrillar amyloid beta-peptide induces apoptotic neuronal cell death: involvement of its C-terminal fusogenic domain

21 January 2018

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Acetyl-L-carnitine arginine amide prevents beta 25-35-induced neurotoxicity in cerebellar granule cells

21 January 2018

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Association of circulating TNF-alpha and IL-6 with ageing and parkinsonism

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Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis

21 January 2018

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FK506 prevents stroke-induced generation of ceramide and apoptosis signaling

21 January 2018

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Ceramide regulates the transcription of cyclooxygenase-2. Evidence for involvement of extracellular signal-regulated kinase/c-Jun N-terminal kinase and p38 mitogen-activated protein kinase pathways

21 January 2018

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Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain

21 January 2018

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Clinical trial of indomethacin in Alzheimer's disease.

21 January 2018

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Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs.

21 January 2018

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Risk of Alzheimer's disease and duration of NSAID use.

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Nonsteroidal anti-inflammatory drugs in Alzheimer's disease.

21 January 2018

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A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease.

21 January 2018

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Effects of memantine and MK-801 on NMDA-induced currents in cultured neurones and on synaptic transmission and LTP in area CA1 of rat hippocampal slices

21 January 2018

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MK-801, memantine and amantadine show neuroprotective activity in the nucleus basalis magnocellularis

21 January 2018

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Early detection of Parkinson's disease. Implications for treatment

21 January 2018

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Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

21 January 2018

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Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease

21 January 2018

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Midbrain dopaminergic neurons are protected from radical induced damage by GDF-5 application. Short communication

21 January 2018

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Short communication: transforming growth factor-beta mediates the neurotrophic effect of fibroblast growth factor-2 on midbrain dopaminergic neurons

21 January 2018

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Transforming growth factor-betas in neurodegenerative disease

21 January 2018

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Nerve growth factor and nootropic drug Cerebrolysin but not fibroblast growth factor can reduce spatial memory impairment elicited by fimbria-fornix transection: short-term study.

21 January 2018

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Early postnatal treatment with peptide preparations influences spatial navigation of young and adult rats

21 January 2018

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Cerebrolysin ameliorates performance deficits, and neuronal damage in apolipoprotein E-deficient mice.

21 January 2018

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21 January 2018

Caspases: enemies within

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Contribution of the ICE family to neurodegeneration

21 January 2018

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Apoptosis. Dead end for neurodegeneration?

21 January 2018

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Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease

21 January 2018

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Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8.

21 January 2018

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

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Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein

21 January 2018

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Of calcium, caspases, and cognitive decline.

21 January 2018

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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

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Caspase inhibition reduces apoptosis and increases survival of nigral transplants

21 January 2018

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Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation

21 January 2018

1 reference

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A serine protease inhibitor, protease nexin I, rescues motoneurons from naturally occurring and axotomy-induced cell death

21 January 2018

1 reference

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Gene therapy for Parkinson's disease: an approach to the prevention or palliation of levodopa-associated motor complications

21 January 2018

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Stable transfection of PC12 cells with estrogen receptor (ERalpha): protective effects of estrogen on cell survival after serum deprivation

21 January 2018

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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

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Translating cell biology into therapeutic advances in Alzheimer's disease

21 January 2018

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CSF neurotransmitter markers in Alzheimer's disease

21 January 2018

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Polymer-encapsulated Schwannoma cells expressing human nerve growth factor promote the survival of cholinergic neurons after a fimbria-fornix transection

21 January 2018

1 reference

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Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons

21 January 2018

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The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor

21 January 2018

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Transplantation of a polymer-encapsulated cell line genetically engineered to release NGF.

21 January 2018

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Polymer-encapsulated genetically modified cells continue to secrete human nerve growth factor for over one year in rat ventricles: behavioral and anatomical consequences

21 January 2018

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AIT-082, a unique purine derivative, enhances nerve growth factor mediated neurite outgrowth from PC12 cells.

21 January 2018

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Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre

21 January 2018

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Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis

21 January 2018

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Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

21 January 2018

1 reference

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Energy metabolism during apoptosis. Bcl-2 promotes survival in hematopoietic cells induced to apoptose by growth factor withdrawal by stabilizing a form of metabolic arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.4.747

Apoptosis is regulated by the rate of glucose transport in an interleukin 3 dependent cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.4.747

Thermodynamics of model prions and its implications for the problem of prion protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.9.4.747

Reduction of ischemic damage in NGF-transgenic mice: correlation with enhancement of antioxidant enzyme activities.

21 January 2018

1 reference

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NGF prevents changes in rat brain glutathione-related enzymes following transection of the septohippocampal pathway.

21 January 2018

1 reference

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21 January 2018

Towards a better aspirin

1 reference

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Effect of idebenone on in vivo serotonin release and serotonergic receptors in young and aged rats

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1517/13543784.9.4.747

1 reference

30 July 2017

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