Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis (Q34074906)

30 July 2017

Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis (English)

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30 July 2017

5

Yi Ren

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30 July 2017

Qiansheng Ren

1

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30 July 2017

Christian Wimmer

2

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30 July 2017

Michael C Chicka

3

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30 July 2017

Shaojing Ye

4

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30 July 2017

Frederick M Hughson

6

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30 July 2017

Sidney W Whiteheart

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30 July 2017

language of work or name

English

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publication date

30 April 2010

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30 July 2017

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30 July 2017

116

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30 July 2017

6

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30 July 2017

869-877

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describes a project that uses

30 July 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2924225/fullTextXML

inferred from PubMed Central ID database lookup

cites work

VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA

1 reference

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Role of vesicle tethering factors in the ER-Golgi membrane traffic.

5 July 2018

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Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

The platelet release reaction: just when you thought platelet secretion was simple

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Munc13-4 regulates granule secretion in human neutrophils

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Doc2 alpha and Munc13-4 regulate Ca(2+) -dependent secretory lysosome exocytosis in mast cells

5 July 2018

1 reference

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Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

5 July 2018

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Rab27b regulates number and secretion of platelet dense granules

5 July 2018

1 reference

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Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4

5 July 2018

1 reference

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Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction

5 July 2018

1 reference

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HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis.

5 July 2018

1 reference

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Analysis of natural killer-cell function in familial hemophagocytic lymphohistiocytosis (FHL): defective CD107a surface expression heralds Munc13-4 defect and discriminates between genetic subtypes of the disease

5 July 2018

1 reference

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UNC-13 interaction with syntaxin is required for synaptic transmission.

5 July 2018

1 reference

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Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells

5 July 2018

1 reference

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Platelet secretory mechanisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Protein-protein interactions in platelet alphaIIbbeta3 signaling

5 July 2018

1 reference

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Regulation of insulin exocytosis by Munc13-1.

5 July 2018

1 reference

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A role for Sec1/Munc18 proteins in platelet exocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Munc13-1 acts as a priming factor for large dense-core vesicles in bovine chromaffin cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Drosophila UNC-13 is essential for synaptic transmission

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Cloning of a novel gene in the human kidney homologous to rat munc13s: its potential role in diabetic nephropathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

SNAREpins: minimal machinery for membrane fusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Regulated secretion in platelets: identification of elements of the platelet exocytosis machinery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Implications of the SNARE hypothesis for intracellular membrane topology and dynamics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Identification of the minimal protein domain required for priming activity of Munc13-1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Flow-cytometric analysis of mouse platelet function

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Rab27a is required for regulated secretion in cytotoxic T lymphocytes

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

UNC-13 is required for synaptic vesicle fusion in C. elegans

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Molecular Mechanisms of Platelet Exocytosis: Requirements for α-Granule Release

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924225

Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 and 4 in lysosome release

28 October 2018

1 reference

12 December 2020

Molecular Basis of Platelet Granule Secretion

1 reference

12 December 2020

Measurement of secretion of serotonin

1 reference

12 December 2020

Proteins of the exocytotic core complex mediate platelet alpha-granule secretion. Roles of vesicle-associated membrane protein, SNAP-23, and syntaxin 4

1 reference

12 December 2020

A critical role for N-ethylmaleimide-sensitive fusion protein (NSF) in platelet granule secretion

1 reference

12 December 2020

The Rab27a effectors JFC1/Slp1 and Munc13-4 regulate exocytosis of neutrophil granules.

1 reference

12 December 2020

Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 in dense core granule release

1 reference

12 December 2020

10.1182/BLOOD-2010-02-270934

Identifiers

DOI

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30 July 2017

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30 July 2017

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